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Paper Information

Journal:   IRANIAN JOURNAL OF POLYMER SCIENCE AND TECHNOLOGY (PERSIAN)   FEBRUARY-MARCH 2008 , Volume 20 , Number 6 (ISSUE NO. 90); Page(s) 515 To 519.
 
Paper: 

STUDY ON MUCOADHESION PROPERTIES OF CHITOSAN

 
 
Author(s):  TAGHIZADEH S.M.*, DAVARI G.
 
* IRAN POLYMER AND PETROCHEMICAL INSTITUTE, TEHRAN, IRAN
 
Abstract: 

Using controlled drug delivery devices is one of the novel methods of drug delivery which is used to perform drug therapy with the minimum side effects. Mucoadhesive polymers are one of these devices. Chitosan is a natural polymer which is a suitable candidate for this purpose due to it is biocompatibility, bioadhesion and high capability to adsorb peptide drugs. Since GI tract has both acidic and basic pH, in this study the interaction between mucin and chitosan as well as swelling of chitosan were investigated in two different media (pH= 5.5 and 7.4). The amount of surface adsorbed mucin was obtained by using spectroscopy. The results have shown that interaction intensity and swelling were pH dependent and reversible.

 
Keyword(s): CHITOSAN, MUCOADHESION, SWELLING, MUCIN, SURFACE ADSORPTION
 
 
References: 
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Click to Cite.
APA: Copy

TAGHIZADEH, S., & DAVARI, G. (2008). STUDY ON MUCOADHESION PROPERTIES OF CHITOSAN. IRANIAN JOURNAL OF POLYMER SCIENCE AND TECHNOLOGY (PERSIAN), 20(6 (ISSUE NO. 90)), 515-519. https://www.sid.ir/en/journal/ViewPaper.aspx?id=102349



Vancouver: Copy

TAGHIZADEH S.M., DAVARI G.. STUDY ON MUCOADHESION PROPERTIES OF CHITOSAN. IRANIAN JOURNAL OF POLYMER SCIENCE AND TECHNOLOGY (PERSIAN). 2008 [cited 2021May11];20(6 (ISSUE NO. 90)):515-519. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=102349



IEEE: Copy

TAGHIZADEH, S., DAVARI, G., 2008. STUDY ON MUCOADHESION PROPERTIES OF CHITOSAN. IRANIAN JOURNAL OF POLYMER SCIENCE AND TECHNOLOGY (PERSIAN), [online] 20(6 (ISSUE NO. 90)), pp.515-519. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=102349.



 
 
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