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Paper Information

Journal:   HORMOZGAN MEDICAL JOURNAL   SPRING 2007 , Volume 11 , Number 1 ; Page(s) 13 To 16.
 
Paper: 

HELICOBACTER PYLORI SEROLOGY IN PREGNANT WOMEN WITH HYPEREMESIS GRAVIDARUM

 
 
Author(s):  ABEDIASL ZH.*, NATEGHI F., ETAATI Z., SOBHANI S.A.R.
 
* SHARIATI HOSPITAL HORMOZGAN UNIVERSITY OF MEDICAL SCIENCES, BANDAR ABBAS, IRAN
 
Abstract: 

Introduction: Hyperemesis gravidarum (HG) is a relatively common problem. Despite its obvious effect on quality of life in pregnancy, it can lead to dangerous complications. This study was conducted to evaluate the hypothesis that there is meaningful association between hyperemesis gravidarum and gastric infection with Helicobacter pylori.
Methods: This is a prospective case-controlstudy in which 90 pregnant women aged 15-37years with gestational age of 6-16 weeks from LMP participated. 40 pregnant women with hypermesis gravidarum were selected from inpatient pregnants of Dr.
Ali Shariati Hospital as cases and 50 normal pregnant from refereres to obstetric clinic of hospital as control group randomly. After filling written consent from, 5 cc venous blood sample was taken for detection of serum IgG and IgM for Helicobacter pylori and IgG> 20 was considered positive. Statistical analysis was performed with the use of t-test. P-value < 0.05 was considered statistically significant.
Results: Seropositivity for Helicobacter pylori was detected in 22 cases out of 40 hyperemetic women (55%) which was not statistically significant. In our study a significant correlation was seen between high BMI and seropositivity for Helicobacter pylori in mothers with hyperemesis gravidarum.
Conclusion: Although infection with Helicobacter Pylori in hyperemetic pregnant women was higher than seronegative ones, it is not statistically significant.

 
Keyword(s): HELICOBACTER PYLORI, HYPEREMESIS GRAVIDARUM, PREGNANCY
 
References: 
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