This study aimed at finding a way for the remediation of toxic and radioactive pollutants. After studying different areas, the researchers succeeded in isolating an Iranian native bacterial strain that could produce a kind of exopolymer in large quantities. This exopolymer plays a key role in metal adsorption; that is, the increase in metal absorption is directly related to the secreted exopolymer. The results of the experiments show that uranium and cadmium uptake by bacterial biomas was 550-800 and 800 mg metal per one gram of the dry weight. Compared with those of other studies, these amounts are remarkable and the microorganism is reported as the second in the world after Citrobacter sp. The results of the investigation on the removal rate of toxic metals and radionuclide from the polluted waste in the bio-reactor revealed that this system is capable of bioremediation of U, Cd, Pb, Ag and Ni as much as >99, 99, 90, 72, and 57%, respectively. Calcium chloride plays a very effective role in the formation of biopolymer flocks and in increasing their precipitation rate in the bioreactor. Consequently, this biopolymer can be used both as a bio-resin and as a bio-precipitator for bioremediation of nuclear wastes.