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Paper Information

Journal:   THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES   FALL 2007 , Volume 11 , Number 3 (44); Page(s) 46 To 50.
 
Paper: 

PREDICTIVE VALUE OF CORONARY ARTERY CALCIFICATION IN CORONARY ARTERY STENOSIS

 
 
Author(s):  SADEGHI M.*, POURMOGHADAS M., ROUHAFZA H.R., SABET B.
 
* 
 
Abstract: 

Background: Early diagnosis of CAD could lead to proper treatment of patients and coronary artery calcification is considered to be a valuable index in detecting coronary artery disease using a noninvasive technique.
Objective: To evaluate the relation between calcification and stenosis of coronary artery.
Methods: This was a cross sectional study in which 760 patients suffering from typical chest pain and as candidates for coronary angiography were evaluated for calcification of coronary artery by fluoroscopy. All patients signed a consent form while the whole procedures were fully explained in a comprehensible language. Following fluoroscopy and angiography, the results were reviewed by two different cardiologists, separately. The presence of any significant stenosis greater than 75% was considered as a sign for severe CAD. The data were analyzed by X2 followed by determination of sensitivity and specificity.
Findings: Abnormal angiogram was found in 402 cases of our patients. In general, the positive and negative predictive values for calcification were 81.8% and 26%, respectively. The positive and negative predictive values were 87.1% and 63.4% in females and 79.7 and 47.3% in males respectively. The highest predictive value was seen in patients below 40 years old (100%). Coronary calcification in patients with abnormal coronary angiogram was found to be 5.4 times higher than those with normal angiogram.
Conclusion: According to our results, the noninvasive fluoroscopic technique for detection of coronary artery calcification could be regarded as a screening tool to reveal significant coronary involvement.

 
Keyword(s): CALCIFICATION, CORONARY VESSELS, CORONARY DISEASE, DIAGNOSIS
 
References: 
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