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Paper Information

Journal:   IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM)   OCTOBER 2007 , Volume 9 , Number 3 (SN 35); Page(s) 229 To 234.
 
Paper: 

EFFECTS OF PURIFIED OMEGA –3 FATTY ACIDS IN POSTMENOPAUSAL WOMEN WITH TYPE 2 DIABETES

 
 
Author(s):  SHIDFAR F.*, YAR AHMADI SH., JALALI M., EFTEKHARI M.H., HOSSEINI SHARIEH, AHARI L.
 
* SCHOOL OF HEALTH, IRAN UNIVERSITY OF MEDICAL SCIENCES
 
Abstract: 

Introduction: Omega 3 fatty acid (03FA) consumption has been shown to reduce risk factors for cardiovascular disease. TYPE 2 diabetes confers an adverse cardiovascular risk profile particularly in women after menopause. The aim of this study was to determine whether a dietary supplement with omega 3 fatty acids affected insulin resistance, glycemic control and cardiovascular risk markers in postmenopausal women with type 2 diabetes. A total of 32 postmenopausal overweight women with diet-controlled type 2 diabetes completed a randomized double blind parallel trial of purified omega 3 fatty acid supplementation (2g/day) versus placebo for 10 weeks. Evaluated were serum triglycerides (TG), HDL-c, total cholesterol (TC) and glucose using the enzymatic method, Insulin by radioimmunoassay and insulin resistance using the Homeostasis Model Assessment method (HOMA-IR) were calculated. Relative to those in the placebo group, TG decreased significantly (P=0.03) in the 03 FA group. 03 FA supplementation had no significant effect on serum LDL-c, HDL-c , glucose and insulin resistance but there was a significant increase in serum insulin and TC in the 03 FA group at the end of study compared to the beginning (P=0.04, P=0.04 respectively). Intake of 2g 03 FA had favorable effects on serum TG and TG/HDL-C, no effect of LDL-C, HDL-C, glucose and insulin resistance but did have an adverse effect on serum insulin and TC. Recommendation of 03FA intake in diabetic postmenopausal women needs further investigation.

 
Keyword(s): OMEGA –3 FATTY ACIDS, POSTMENOPAUSAL WOMEN ,TYPE2 DIABETES , LIPOPROTEIN , GLUCOSE
 
 
References: 
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Citations: 
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+ Click to Cite.
APA: Copy

SHIDFAR, F., & YAR AHMADI, S., & JALALI, M., & EFTEKHARI, M., & HOSSEINI, S., & AHARI, L. (2007). EFFECTS OF PURIFIED OMEGA –3 FATTY ACIDS IN POSTMENOPAUSAL WOMEN WITH TYPE 2 DIABETES. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), 9(3 (SN 35)), 229-234. https://www.sid.ir/en/journal/ViewPaper.aspx?id=101604



Vancouver: Copy

SHIDFAR F., YAR AHMADI SH., JALALI M., EFTEKHARI M.H., HOSSEINI SHARIEH, AHARI L.. EFFECTS OF PURIFIED OMEGA –3 FATTY ACIDS IN POSTMENOPAUSAL WOMEN WITH TYPE 2 DIABETES. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM). 2007 [cited 2021June21];9(3 (SN 35)):229-234. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=101604



IEEE: Copy

SHIDFAR, F., YAR AHMADI, S., JALALI, M., EFTEKHARI, M., HOSSEINI, S., AHARI, L., 2007. EFFECTS OF PURIFIED OMEGA –3 FATTY ACIDS IN POSTMENOPAUSAL WOMEN WITH TYPE 2 DIABETES. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), [online] 9(3 (SN 35)), pp.229-234. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=101604.



 
 
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