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Paper Information

Journal:   HORMOZGAN MEDICAL JOURNAL   SPRING 2006 , Volume 10 , Number 1; Page(s) 83 To 88.
 
Paper: 

PREVALENCE OF OPIOID USE BASED ON URINE SAMPLE AMONG MEN REFERRED TO ONE OF THE CLINICAL LABORATORIES IN KERMAN, IRAN

 
 
Author(s):  DIVSALAR K.*, NAKHAEI N., MEYMANDI M.SH., DABIRI SH., KARIMI AFSHAR R.
 
* NEUROSCIENCE RESEARCH CENTER, KERMAN UNIVERSITY OF MEDICAL SCIENCES KERMAN, IRAN
 
Abstract: 

Comparing to other health problems, substance use epidemiology is a new area of research in Iran. The aim of this study was to determine the prevalence of opioid use among referees to a clinical laboratory by drug testing.
Methods: In this cross-sectional study, the urine sample of 1120 consecutive individuals referred to a major clinical laboratory in Kerman city were tested for opioid metabolites anonymously. At first, a screening test was done on samples (chromatographic Immunoassay test, Enison, U.K) and then solid-liquid column chromatography and thin layer chromatography (Sam phannavar, Tehran, Iran) was done on positive samples as a confirmatory test. The results were analyzed using Chi-Square test and descriptive methods.
Results: Ninety-three percent of subjects were urban dwellers and the mean (±SD) age of the sample studied was 46.5 (±16.5). In 28.4% (318) of the specimens the screening test became positive and thin layer chromatography confirmed half of them as true positive. So, 14.4% of samples were positive regarding opioid metabolites.
Conclusion: Although individuals attending laboratory clinics may not be a representative sample of the whole Kermani population, but the relatively high figures obtained have significant implications for further research.

 
Keyword(s): OPIOID PEPTIDES, URINE, MEN
 
References: 
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