Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   PAJOUHESH DAR PEZESHKI   SPRING 2007 , Volume 31 , Number 1; Page(s) 99 To 101.
 
Paper: 

PRIMARY PLASMA CELL LEUKEMIA: EFFECTIVE TREATMENT WITH INTERMEDIATE DOSE MELPHALAN

 
 
Author(s):  GHADYANI M.*, RAHIMI H., REZVANI H., ATARIAN H.
 
* DEPARTMENT OF HEMATOLOGY AND ONCOLOGY, SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES
 
Abstract: 

Primary Plasma cell Leukemia (PCL) is a rare disease with no standard treatment, although, combination chemotherapy, BMT and intermediate dose melphalan have been shown to be effective, in some case reports. Patients usually present with anemia, thrombocytopenia, hypercalcemia, and renal failure.

Diagnosis is confirmed by peripheral and bone marrow examination. We recently had a case in our department. A 43 years old gentleman presented with history of fatigue, weakness, weight loss, dyspnea and bone pain. Diagnosis of PCL was confirmed by PBS and bone marrow exam. The patient was treated using single intermediate dose melphalan (60 mg/m2/ IV) plus Dexamethasone with G–CSF support; after 3 weeks, complete remission was achieved.

In the last visit, done 9 months after treatment, he was doing well clinically and his Lab data were normal.

This case report confirmed the efficacy of intermediate dose of melphalan in the management of plasma cell leukemia.

 
Keyword(s): PLASMA CELL LEUKEMIA, MELPHALAN, INTERMEDIATE DOSE
 
 
References: 
  • Not Registered.
  •  
  •  
 
Citations: 
  • Not Registered.
 
+ Click to Cite.
APA: Copy

GHADYANI, M., & RAHIMI, H., & REZVANI, H., & ATARIAN, H. (2007). PRIMARY PLASMA CELL LEUKEMIA: EFFECTIVE TREATMENT WITH INTERMEDIATE DOSE MELPHALAN. PAJOUHESH DAR PEZESHKI, 31(1), 99-101. https://www.sid.ir/en/journal/ViewPaper.aspx?id=95909



Vancouver: Copy

GHADYANI M., RAHIMI H., REZVANI H., ATARIAN H.. PRIMARY PLASMA CELL LEUKEMIA: EFFECTIVE TREATMENT WITH INTERMEDIATE DOSE MELPHALAN. PAJOUHESH DAR PEZESHKI. 2007 [cited 2021October28];31(1):99-101. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=95909



IEEE: Copy

GHADYANI, M., RAHIMI, H., REZVANI, H., ATARIAN, H., 2007. PRIMARY PLASMA CELL LEUKEMIA: EFFECTIVE TREATMENT WITH INTERMEDIATE DOSE MELPHALAN. PAJOUHESH DAR PEZESHKI, [online] 31(1), pp.99-101. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=95909.



 
 
Persian Abstract Yearly Visit 40
 
 
Latest on Blog
Enter SID Blog