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Paper Information

Journal:   OFOGH-E-DANESH   winter 2019 , Volume 25 , Number 1 ; Page(s) 22 To 28.
 
Paper: 

The Protective Effect Of High Intensity Interval Training Preconditioning On Ischemia Reperfusion-Injury In Ageing Rats

 
 
Author(s):  Fatahi A., Azizbeigi K., Ranjbar K.*, Mohammadzadeh K.
 
* Department of Physical Education and Sports Science, Bandar Abbas Azad University, Bandar Abbas, Iran
 
Abstract: 
Aims: The heart resistance to ischemia decreases with aging. Exercise training by preconditioning decreases ischemia reperfusion-injury. Therefore the aim of the present study was to investigate the effect of high intensity interval training on ischemia reperfusion-injury in ageing rats. Material & methods: In this experimental study, 20 ageing male wistar rats (20 months old) were randomly distributed in control (n=10) and training groups (n=10). The training group performed high intensity interval training for 8 weeks. 48 hours after last exercise session, rats were subjected to ischemia via LAD artery ligation for 30 min followed by 90 min reperfusion. After reperfusion, stress oxidative indices and infarction size were measured. To evaluate the difference between groups, independent t-test was used with significant level of p ≤ 0. 05. Findings: GPX, Catalase and MDA were not different between two groups, but GSH was more in training rats compared with control groups (p=0. 05). Infarction size in response to training decreased by 7% compared with control rats (p=0. 001). Conclusion: The results of this study showed that 8 weeks of high intensity interval training probably decrease ischemia reperfusion injury by antioxidant capacity promotion.
 
Keyword(s): Myocardial Ischemia,Exercise,Aging
 
 
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APA: Copy

FATAHI, A., & AZIZBEIGI, K., & RANJBAR, K., & MOHAMMADZADEH, K. (2019). The Protective Effect of High Intensity Interval Training Preconditioning on Ischemia Reperfusion-Injury in Ageing Rats. OFOGH-E-DANESH, 25(1 ), 22-28. https://www.sid.ir/en/journal/ViewPaper.aspx?id=707601



Vancouver: Copy

FATAHI A., AZIZBEIGI K., RANJBAR K., MOHAMMADZADEH K.. The Protective Effect of High Intensity Interval Training Preconditioning on Ischemia Reperfusion-Injury in Ageing Rats. OFOGH-E-DANESH. 2019 [cited 2022January28];25(1 ):22-28. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=707601



IEEE: Copy

FATAHI, A., AZIZBEIGI, K., RANJBAR, K., MOHAMMADZADEH, K., 2019. The Protective Effect of High Intensity Interval Training Preconditioning on Ischemia Reperfusion-Injury in Ageing Rats. OFOGH-E-DANESH, [online] 25(1 ), pp.22-28. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=707601.



 
 
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