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Paper Information

Journal:   IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES   JULY 2018 , Volume 21 , Number 7; Page(s) 651 To 659.
 
Paper: 

Interaction of viral oncogenic proteins with the Wnt signaling pathway

 
 
Author(s):  KHANIZADEH SAYYAD, HASANVAND BANAFSHEH, Lashgarian Hamed Esmaeil, ALMASIAN MOHAMMAD, GOUDARZI GHOLAMREZA*
 
* Department of Microbiology, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran
 
Abstract: 
It is estimated that up to 20% of all types of human cancers worldwide are attributed to viruses. The genome of oncogenic viruses carries genes that have protein products that act as oncoproteins in cell proliferation and transformation. The modulation of cell cycle control mechanisms, cellular regulatory and signaling pathways by oncogenic viruses, plays an important role in viral carcinogenesis. Different signaling pathways play a part in the carcinogenesis that occurs in a cell. Among these pathways, the Wnt signaling pathway plays a predominant role in carcinogenesis and is known as a central cellular pathway in the development of tumors. There are three Wnt signaling pathways that are well identified, including the canonical or Wnt/β-catenin dependent pathway, the noncanonical or β-catenin-independent planar cell polarity (PCP) pathway, and the noncanonical Wnt/Ca2+ pathway. Most of the oncogenic viruses modulate the canonical Wnt signaling pathway. This review discusses the interaction between proteins of several human oncogenic viruses with the Wnt signaling pathway.
 
Keyword(s): β-catenin,Canonical pathway,Carcinogenesis,Oncogenic viruses,Wnt signaling
 
 
References: 
 
Citations: 
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APA: Copy

KHANIZADEH, S., & HASANVAND, B., & Lashgarian, H., & ALMASIAN, M., & GOUDARZI, G. (2018). Interaction of viral oncogenic proteins with the Wnt signaling pathway. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 21(7), 651-659. https://www.sid.ir/en/journal/ViewPaper.aspx?id=687509



Vancouver: Copy

KHANIZADEH SAYYAD, HASANVAND BANAFSHEH, Lashgarian Hamed Esmaeil, ALMASIAN MOHAMMAD, GOUDARZI GHOLAMREZA. Interaction of viral oncogenic proteins with the Wnt signaling pathway. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES. 2018 [cited 2021October16];21(7):651-659. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=687509



IEEE: Copy

KHANIZADEH, S., HASANVAND, B., Lashgarian, H., ALMASIAN, M., GOUDARZI, G., 2018. Interaction of viral oncogenic proteins with the Wnt signaling pathway. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, [online] 21(7), pp.651-659. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=687509.



 
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