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Journal:   IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES   november 2017 , Volume 20 , Number 11; Page(s) 1282 To 1286.
 
Paper: 

First Report Of Oxa-143-Lactamase Producing Acinetobacter Baumannii In Qom, Iran

 
 
Author(s):  Sarikhani Zohreh, Nazari Razieh*, Nateghi Rostami Mahmoud
 
* Department of Microbiology, Qom Azad University, Qom, Iran
 
Abstract: 
Objective(s): Antibiotic resistance in Acinetobacter baumannii and outbreaks caused by this organism have been reported from several areas of the world. The present study aimed at determining the antibiotic susceptibility profiles and the distribution of OXA-type beta-lactamases among Iranian Acinetobacter baumannii isolates from Qom of Iran. Materials and Methods: For this study, 108 non-duplicate A. baumannii isolates were obtained from clinical specimens in four teaching hospitals in Qom in the central of Iran. The antimicrobial susceptibility of isolates was tested by standard disk diffusion and prevalence of bla OXA genes was investigated by PCR method. Results: Among 97 carbapenem non-susceptible isolates of A. baumannii, 90. 72% (88 isolates) isolates showed extensive drug resistance to multiple antibiotics. Among carbapenem resistant isolates, 100% carried blaOXA-51-like, 82. 47% carried blaOXA-23-like, 55. 67% carried blaOXA-58-like, 22. 68% carried blaOXA-40-like and 14. 43% had blaOXA-143-like resistance genes. Conclusion: This study demonstrated high genetic diversity of OXA genes among isolates of A. baumannii in Qom, Iran.
 
Keyword(s): Acinetobacter baumannii blaOXA-143,Carbapenem resistance,Iran,Polymerase chain-reaction
 
 
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APA: Copy

Sarikhani, Z., & NAZARI, R., & NATEGHI ROSTAMI, M. (2017). First report of OXA-143-lactamase producing Acinetobacter baumannii in Qom, Iran. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 20(11), 1282-1286. https://www.sid.ir/en/journal/ViewPaper.aspx?id=684934



Vancouver: Copy

Sarikhani Zohreh, NAZARI RAZIEH, NATEGHI ROSTAMI MAHMOUD. First report of OXA-143-lactamase producing Acinetobacter baumannii in Qom, Iran. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES. 2017 [cited 2022May24];20(11):1282-1286. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=684934



IEEE: Copy

Sarikhani, Z., NAZARI, R., NATEGHI ROSTAMI, M., 2017. First report of OXA-143-lactamase producing Acinetobacter baumannii in Qom, Iran. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, [online] 20(11), pp.1282-1286. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=684934.



 
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