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Paper Information

Journal:   INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)   november 2016 , Volume 14 , Number 11; Page(s) 687 To 690.
 
Paper: 

Efficacy of Intrauterine infusion of granulocyte colony stimulating factor on patients with history of implantation failure: A randomized control trial

 
 
Author(s):  EFTEKHAR MARYAM, MIRAJ SEPIDEH*, FARID MOJTAHEDI MARYAM, NEGHAB NOSRAT
 
* Department of Obstetrics and Gynecology, School of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran
 
Abstract: 
Background: Although pregnancy rate in in vitro fertilization-embryo transfer (IVF-ET) cycles has been increased over the preceding years, but the majority of IVF-ET cycles still fail. Granulocyte colony stimulating factor (GCSF) is a glycoprotein that stimulates cytokine growth factor and induces immune system which may improve pregnancy rate in women with history of implantation failure. Objective: The aim of this study was to evaluate GCSF ability to improve pregnancy rate in women with history of implantation failure Materials and Methods: 0. 5 ml (300 μ g/ml) GCSF was infused intrauterine in intervention group. Pregnancy outcomes were assessed based on clinical pregnancy. Results: The mean age of participants was 31. 95± 4. 71 years old. There were no significant differences between demographic characteristics in two groups (p>0. 05). The pregnancy outcome in GCSF group was improved significantly (p=0. 043). Conclusion: GCSF can improve pregnancy outcome in patients with history of implantation failure.
 
Keyword(s): GCSF,Pregnancy rate,In vitro fertilization
 
 
References: 
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Citations: 
 
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APA: Copy

EFTEKHAR, M., & MIRAJ, S., & FARID MOJTAHEDI, M., & NEGHAB, N. (2016). Efficacy of Intrauterine infusion of granulocyte colony stimulating factor on patients with history of implantation failure: A randomized control trial. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 14(11), 687-690. https://www.sid.ir/en/journal/ViewPaper.aspx?id=666245



Vancouver: Copy

EFTEKHAR MARYAM, MIRAJ SEPIDEH, FARID MOJTAHEDI MARYAM, NEGHAB NOSRAT. Efficacy of Intrauterine infusion of granulocyte colony stimulating factor on patients with history of implantation failure: A randomized control trial. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE). 2016 [cited 2021September24];14(11):687-690. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=666245



IEEE: Copy

EFTEKHAR, M., MIRAJ, S., FARID MOJTAHEDI, M., NEGHAB, N., 2016. Efficacy of Intrauterine infusion of granulocyte colony stimulating factor on patients with history of implantation failure: A randomized control trial. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), [online] 14(11), pp.687-690. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=666245.



 
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