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Paper Information

Journal:   INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)   DECEMBER 2016 , Volume 14 , Number 12; Page(s) 729 To 736.
 
Paper: 

ANTIOXIDANT SUPPLEMENTS AND SEMEN PARAMETERS: AN EVIDENCE BASED REVIEW

 
 
Author(s):  AHMADI SEDIGHEH, BASHIRI REIHANEH, GHADIRI ANARI AKRAM, NAJARZADEH AZADEH*
 
* NUTRITION AND FOOD SECURITY RESEARCH CENTER, SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, YAZD, IRAN
 
Abstract: 

Many studies have focused on male infertility. There is limited evidence about the influence of nutrition on quality of semen. Approximately, 30-80% of infertility cases are caused by oxidative stress and decreased level of seminal total antioxidant capacity. This study was aimed to review the effects of oral antioxidant supplements on improving major semen parameters such as sperm concentration, motility, morphology, DNA damage, and fertility rate. Data were extracted from PubMed and Google scholar database by using the terms "antioxidant", "multivitamin", "carnitine", "CoQ10", "vitamin C", "vitamin E", "zinc", "folic acid", "N-acetyl cysteine" and "selenium" combined with "male infertility", "semen", and "sperm" to generate a set of relevant citations. Supplements such as CoQ10 and alpha-tocopherol significantly improve sperm count. Also, carnitine has positive effects on sperm motility and morphology. Simultaneous administration of vitamin E and vitamin C reduces the sperm DNA damage. However, in some studies, one or more factors have not changed substantially. In most of the studies, antioxidant supplementation improved the number, motility, morphology and sometimes DNA integrity of sperm. The present study showed that antioxidant supplements, especially a combination of antioxidants such as vitamin C, vitamin E, and CoQ10 intake can effectively improve semen parameters in infertile men.
 
Keyword(s): MALE INFERTILITY, SEMEN, ANTIOXIDANTS, CARNITINE, COENZYME Q10 (COQ10), VITAMINS
 
 
References: 
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Citations: 
 
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APA: Copy

AHMADI, S., & BASHIRI, R., & GHADIRI ANARI, A., & NAJARZADEH, A. (2016). ANTIOXIDANT SUPPLEMENTS AND SEMEN PARAMETERS: AN EVIDENCE BASED REVIEW. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 14(12), 729-736. https://www.sid.ir/en/journal/ViewPaper.aspx?id=557696



Vancouver: Copy

AHMADI SEDIGHEH, BASHIRI REIHANEH, GHADIRI ANARI AKRAM, NAJARZADEH AZADEH. ANTIOXIDANT SUPPLEMENTS AND SEMEN PARAMETERS: AN EVIDENCE BASED REVIEW. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE). 2016 [cited 2021November29];14(12):729-736. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=557696



IEEE: Copy

AHMADI, S., BASHIRI, R., GHADIRI ANARI, A., NAJARZADEH, A., 2016. ANTIOXIDANT SUPPLEMENTS AND SEMEN PARAMETERS: AN EVIDENCE BASED REVIEW. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), [online] 14(12), pp.729-736. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=557696.



 
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