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Paper Information

Journal:   BINA   Winter 2004 , Volume 9 , Number 2 (34); Page(s) 122 To 129.
 
Paper: 

LONG-TERM RESULTS OF ENDORESECTION OF POSTERIOR CHOROIDAL MELANOMA

 
 
Author(s):  KARKHANEH R., CHAMS H., YAZDIZADEH H., NILI AHMADABADI MAHDI, VALAEI NASER
 
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Abstract: 

Purpose: To determine the long-term visual and mortality outcomes of endoresection for treatment of malignant posterior choroidal melanoma.
Methods: This before and after clinical trial included 20 eyes of 20 patients with a diagnosis of posterior choroidal melanoma confirmed by indirect ophthalmoscopy and A and B ultrasonography. All tumors were medium sized according to measures of Collaborated Ocular Melanoma Study and no one had extra ocular metastases. After obtaining informed consent, the eyes underwent vitrectomy and endoresection of the tumors. Characteristics of the patients and tumors, visual acuity before and after surgery, intraoperative and postoperative complications, and enucleation rates were recorded. Patients were followed for 22 to 108 months (mean: 67.4±36.1).
Results: Of 20 patients, 13 (65%) were male. Mean age was 47.1±16 years. Overall, 5 (25%) eyes were enucleatedincluding 2 eyes (10%) due to severe intraoperative bleeding, 1 eye (5%) due to recurrence of intraocular melanoma, 1 eye (5%) because of a new focus of the tumor, and 1 eye (5%) secondary to intolerable pain. Final visual acuity of 15saved eyes was 20/200 in one eye (6.7%), counting fingers in 8 eyes (52.3%), hand motion in 3 eyes (20%), and no light perception in 3 eyes (15%).
Conclusion: Endresection of posterior choroidal melanoma is a reasonable globe saving treatment modality. Distant metastasis of choroidal melanoma is an infrequent result of this procedure.

 
Keyword(s): ENDORESECTION, MELANOMA, METASTASIS
 
References: 
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