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Journal:   IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ)   JANUARY 2016 , Volume 18 , Number 1; Page(s) 0 To 0.
 
Paper: 

Factors Associated With Serum Albumin In Diabetes Mellitus Type 2 With Microalbuminuria Using Non-Normal Mixed Models: A Prospective Cohort Study

 
 
Author(s):  Khoundabi Batoul, Kazemnejad Anoshirvan*, Mansourian Marjan, Faghihimani Elham
 
* DEPARTMENT OF BIOSTATISTICS, FACULTY OF MEDICAL SCIENCES, TARBIAT MODARES UNIVERSITY, TEHRAN, IR IRAN
 
Abstract: 
Background: The globally increasing epidemic of diabetes will lead to serious problems including diabetic nephropathy and kidney diseases in near future. The first clinical diagnosable stage in a diabetic kidney disease is microalbuminuria (urinary albumin excretion of 30 - 300 g/24 hours).Objectives: This prospective cohort study investigated the risk factors of microalbuminuria in patients with type 2 diabetes who had been registered in endocrine and metabolism research center in Isfahan city, Iran.Patients and Methods: This prospective cohort study was performed on 90 diabetic type 2 patients with microalbuminuria, who were selected according to the consecutive sample selection method during 6 years. Data were collected through regular and systematic measurements of serum albumin as the response variable and body mass index, systolic and diastolic blood pressure, the duration of diabetes, glycosylated hemoglobin (HbA1c), total cholesterol, triglyceride (TG), fasting blood sugar (FBS), low-density lipoprotein (LDL), and high-density lipoprotein (HDL) as the related factors. Non-normal mixed models were used to investigate the impact of effective factors on the amount of excreted serum albumin.Results: According to the deviance information criterion (DIC=56.2), the non-normal mixed effects model with the skewed t distribution had a best fit and indicated that HbA1c, HDL and total cholesterol had a significant effect on the amount of albumin in urine (P<0.05).Conclusions: Using nonnormal mixed models may lead to the best results as compared to common normality assumption.
 
Keyword(s): SERUM ALBUMIN, DIABETES MELLITUS TYPE 2, RISK FACTORS
 
 
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APA: Copy

KHOUNDABI, B., & KAZEMNEJAD, A., & MANSOURIAN, M., & FAGHIHIMANI, E. (2016). FACTORS ASSOCIATED WITH SERUM ALBUMIN IN DIABETES MELLITUS TYPE 2 WITH MICROALBUMINURIA USING NON-NORMAL MIXED MODELS: A PROSPECTIVE COHORT STUDY. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), 18(1), 0-0. https://www.sid.ir/en/journal/ViewPaper.aspx?id=521425



Vancouver: Copy

KHOUNDABI BATOUL, KAZEMNEJAD ANOSHIRVAN, MANSOURIAN MARJAN, FAGHIHIMANI ELHAM. FACTORS ASSOCIATED WITH SERUM ALBUMIN IN DIABETES MELLITUS TYPE 2 WITH MICROALBUMINURIA USING NON-NORMAL MIXED MODELS: A PROSPECTIVE COHORT STUDY. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ). 2016 [cited 2022July04];18(1):0-0. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=521425



IEEE: Copy

KHOUNDABI, B., KAZEMNEJAD, A., MANSOURIAN, M., FAGHIHIMANI, E., 2016. FACTORS ASSOCIATED WITH SERUM ALBUMIN IN DIABETES MELLITUS TYPE 2 WITH MICROALBUMINURIA USING NON-NORMAL MIXED MODELS: A PROSPECTIVE COHORT STUDY. IRANIAN RED CRESCENT MEDICAL JOURNAL (IRCMJ), [online] 18(1), pp.0-0. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=521425.



 
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