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Paper Information

Journal:   JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS)   AUGUST 2016 , Volume 18 , Number 8; Page(s) 48 To 53.
 
Paper: 

COMPARISON OF THE SERUM TOTAL BILE ACIDS AND CHOLESTEROL LEVELS IN BREAST CANCER PATIENTS WITH CONTROL GROUP

 
 
Author(s):  FADAEIPOUR S., BABAEI Z., PARSIAN H.*, MOTEVALIZADEH ARDEKANI A., NIKBAKHSH N.
 
* DEPARTMENT OF BIOCHEMISTRY, FACULTY OF MEDICINE, BABOL UNIVERSITY OF MEDICAL SCIENCES, BABOL, I.R. IRAN
 
Abstract: 

BACKGROUND AND OBJECTIVE: Identification of breast cancer risk factors is very important. Cholesterol by acting on tumor cells is considered as one of the risk factors for breast cancer. The conversion of cholesterol to bile acids is one of the major mechanisms of cholesterol excretion from body. In this study, total bile acids and cholesterol concentrations were evaluated in breast cancer patients.
METHODS: In this case-control study, 109 of patients who breast cancer was confirmed by pathological examination and 109 healthy subjects who had normal physical exam and negative mammograms to rule out breast cancer were studied. Fasting serum total bile acids and cholesterol levels were measured enzymatically and then the data were analyzed.
FINDINGS: The mean of total bile acids in breast cancer patients and control group were 11.67±0.92 and 13.36±0.81
mmol/l, respectively (p<0.05). Mean of cholesterol levels in breast cancer patients was 316.98±15.35 mg/dl and control group was 212.08±5.79 mg/dl (p<0.001). CONCLUSION: According to the results, it appears that lower amounts of body cholesterol are converted to bile acids in breast cancer patients.

 
Keyword(s): BREAST CANCER, TOTAL BILE ACIDS, CHOLESTEROL
 
 
References: 
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+ Click to Cite.
APA: Copy

FADAEIPOUR, S., & BABAEI, Z., & PARSIAN, H., & MOTEVALIZADEH ARDEKANI, A., & NIKBAKHSH, N. (2016). COMPARISON OF THE SERUM TOTAL BILE ACIDS AND CHOLESTEROL LEVELS IN BREAST CANCER PATIENTS WITH CONTROL GROUP. JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS), 18(8), 48-53. https://www.sid.ir/en/journal/ViewPaper.aspx?id=520492



Vancouver: Copy

FADAEIPOUR S., BABAEI Z., PARSIAN H., MOTEVALIZADEH ARDEKANI A., NIKBAKHSH N.. COMPARISON OF THE SERUM TOTAL BILE ACIDS AND CHOLESTEROL LEVELS IN BREAST CANCER PATIENTS WITH CONTROL GROUP. JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS). 2016 [cited 2021October28];18(8):48-53. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=520492



IEEE: Copy

FADAEIPOUR, S., BABAEI, Z., PARSIAN, H., MOTEVALIZADEH ARDEKANI, A., NIKBAKHSH, N., 2016. COMPARISON OF THE SERUM TOTAL BILE ACIDS AND CHOLESTEROL LEVELS IN BREAST CANCER PATIENTS WITH CONTROL GROUP. JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS), [online] 18(8), pp.48-53. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=520492.



 
 
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