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Paper Information

Journal:   NEUROSCIENCE JOURNAL OF SHEFAYE KHATAM   WINTER 2014 , Volume 2 , Number 1; Page(s) 69 To 74.
 
Paper: 

LAMININ POSITION AS ONE OF THE IMPORTANT COMPONENTS OF THE EXTRACELLULAR MATRIX IN TISSUE ENGINEERING OF NERVOUS SYSTEM

 
DOI: 

10.18869/acadpub.shefa.2.1.69

 
Author(s):  MOHAMMAD SADEGHI SHAHIN, SAHAB NEGAH SAJAD, KHAKSAR ZABIHOLLAH*, KAZEMI HADI, ALIGHOLI HADI
 
* HISTOLOGY AND EMBRYOLOGY GROUP, BASIC SCIENCE DEPARTMENT, FACULTY OF VETERINARY MEDICINE, SHIRAZ UNIVERSITY, SHIRAZ, IRAN
 
Abstract: 

Introduction: Brain damage is often irreversible due to poor brain's self-repairing ability. New treatment strategies focused on stem cell therapy and 3-dimension matrix for brain tissue injury. The extracellular matrix (ECM) of animal tissues is a complex mixture of macromolecules that play an essential instructional role in the development of tissues and organs. Therefore, tissue engineering approaches rely on the need to present the correct cues to cells and to guide them to maintain tissue-specific functions. Recent research efforts on ECM have showed various sequences and motifs, which play key roles in improvement of the brain function after injury.
Conclusion: Small motif from ECM molecules can mimic some of the biological functions of their large molecules. Peptides sequences and motifs laminin can be linked to various biomaterials scaffolds and provide the cells with mechanical support. This may ensure appropriate cell growth that aids the formation of the correct tissue structure.

 
Keyword(s): LAMININ, EXTRACELLULAR MATRIX, TISSUE ENGINEERING, NERVOUS SYSTEM
 
 
References: 
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Citations: 
 
+ Click to Cite.
APA: Copy

MOHAMMAD SADEGHI, S., & SAHAB NEGAH, S., & KHAKSAR, Z., & KAZEMI, H., & ALIGHOLI, H. (2014). LAMININ POSITION AS ONE OF THE IMPORTANT COMPONENTS OF THE EXTRACELLULAR MATRIX IN TISSUE ENGINEERING OF NERVOUS SYSTEM. NEUROSCIENCE JOURNAL OF SHEFAYE KHATAM, 2(1), 69-74. https://www.sid.ir/en/journal/ViewPaper.aspx?id=512020



Vancouver: Copy

MOHAMMAD SADEGHI SHAHIN, SAHAB NEGAH SAJAD, KHAKSAR ZABIHOLLAH, KAZEMI HADI, ALIGHOLI HADI. LAMININ POSITION AS ONE OF THE IMPORTANT COMPONENTS OF THE EXTRACELLULAR MATRIX IN TISSUE ENGINEERING OF NERVOUS SYSTEM. NEUROSCIENCE JOURNAL OF SHEFAYE KHATAM. 2014 [cited 2021October18];2(1):69-74. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=512020



IEEE: Copy

MOHAMMAD SADEGHI, S., SAHAB NEGAH, S., KHAKSAR, Z., KAZEMI, H., ALIGHOLI, H., 2014. LAMININ POSITION AS ONE OF THE IMPORTANT COMPONENTS OF THE EXTRACELLULAR MATRIX IN TISSUE ENGINEERING OF NERVOUS SYSTEM. NEUROSCIENCE JOURNAL OF SHEFAYE KHATAM, [online] 2(1), pp.69-74. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=512020.



 
 
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