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Paper Information

Journal:   IRANIAN JOURNAL OF DERMATOLOGY   SPRING 2004 , Volume 3 , Number 3 (27); Page(s) 152 To 155.
 
Paper: 

SERUM ANTIBODY LEVELS TO HELICOBACTER PYLORI IN PATIENTS WITH RECURRENT APHTHOUS STOMATITIS

 
 
Author(s):  RASHIDI T.*, ALAMDARI MAHD A.D., HAMZEH ZADEH A., TALEBI R.
 
* Department of Dermatology, Urmia University of Medical Sciences
 
Abstract: 

Background: Recurrent aphthous stomatitis (RAS) is a common disease which several etiologic factors have been considered for it. The infectious agents and immunological factors are the most suspected causes. Recently a few studies with varied results have been done to clarify the role of Helicobacter pylori (H.pylori) in etiology of RAS.

Objective: To find correlations between serum IgG and IgA levels to Helicobacter pylori and RAS.

Patients & Methods: A total number of 29 patients with RAS referred to Urmia Skin Hospital were included in this case-control study. Control group consisted of 57 persons and was chosen from healthy individuals. Blood samples were taken and blood levels of IgG and IgA antibodies of patients and control were measured by ELISA method and collected data were analyzed by chi-square test.

Results: IgG antibodies to H.pylori were found in the sera of %75.9 of RAS patients and %66.7 of controls. IgA antibodies were detected in %51.9 of RAS and %70.9 of controls. These differences were not statistically significant.

Conclusion: There was no significant difference between IgG and IgA levels to Helicobacter pylori in patients with RAS compared to control group.

 

 

 

 
Keyword(s): RECURRENT APHTHOUS STOMATITIS, HELICOBACTER PYLORI, SERUM ANTIBODIES
 
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