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Paper Information

Journal:   IRANIAN JOURNAL OF DERMATOLOGY   SPRING 2004 , Volume 3 , Number 3 (27); Page(s) 136 To 139.
 
Paper: 

EFFICACY OF COMBINED TRIPLE THERAPY (PARAMOMYCIN OINTMENT, CRYOTHERAPY AND INTRALESIONAL GLUCANTIME) IN COMPARISON WITH INTRALESIONAL GLUCANTIME FOR THE TREATMENT OF ACUTE CUTANEOUS LEISHMANIASIS

 
 
Author(s):  NILFOROUSHZADEH MOHAMMAD ALI*, MALEK AFZALI BEHESHTEH, JAFARI F.
 
* CENTER FOR RESEARCH AND TRAINING IN SKIN DISEASES AND LEPROSY, TEHRAN UNIVERSITY OF MEDICAL SCIENCES
 
Abstract: 

Background: In spite of different methods of treatment, there is not a simple, safe and complete curative treatment for cutaneous leishmaniasis (CL), yet.
Objective: To compare the efficacy of intralesional Glucantime injection alone, with the combined triple therapy of cryotherapy, paramomycm ointment and intralesional Glucantime in the treatment of CL. Patients & Methods: 157 patients with CL were randomly allocated into two groups, 81 patients in group I were injected with intralesional Glucantime (twice a week up to

healing of the lesions or maximum 6 weeks). 76 patients in group 2 were treated with paramomycin ointment (15% in 10% urea, twice a day), cryotherapy (maximum 3 times 2 weeks apart and injection of intralesional Glucantime (once a week), for the same period as group 1.
Results: After 6 weeks, complete cure rate in group 2 (89.5%) was significantly more than group 1 (70.4%) (P<0.05).

Conclusion: Our results indicating of more efficacy of the triple therapy is in accordance with the previous studies of combined cryotherapy and paramomycin. It could be recommended as a better treatment modality for CL wherever possible.

 

 

 

 
Keyword(s): LEISHMANIASIS, GLUCANTIME, CRYOTHERAPY, PARAMOMYCIN
 
 
References: 
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APA: Copy

NILFOROUSHZADEH, M., & MALEK AFZALI, B., & JAFARI, F. (2004). EFFICACY OF COMBINED TRIPLE THERAPY (PARAMOMYCIN OINTMENT, CRYOTHERAPY AND INTRALESIONAL GLUCANTIME) IN COMPARISON WITH INTRALESIONAL GLUCANTIME FOR THE TREATMENT OF ACUTE CUTANEOUS LEISHMANIASIS. IRANIAN JOURNAL OF DERMATOLOGY, 3(3 (27)), 136-139. https://www.sid.ir/en/journal/ViewPaper.aspx?id=48109



Vancouver: Copy

NILFOROUSHZADEH MOHAMMAD ALI, MALEK AFZALI BEHESHTEH, JAFARI F.. EFFICACY OF COMBINED TRIPLE THERAPY (PARAMOMYCIN OINTMENT, CRYOTHERAPY AND INTRALESIONAL GLUCANTIME) IN COMPARISON WITH INTRALESIONAL GLUCANTIME FOR THE TREATMENT OF ACUTE CUTANEOUS LEISHMANIASIS. IRANIAN JOURNAL OF DERMATOLOGY. 2004 [cited 2021May15];3(3 (27)):136-139. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=48109



IEEE: Copy

NILFOROUSHZADEH, M., MALEK AFZALI, B., JAFARI, F., 2004. EFFICACY OF COMBINED TRIPLE THERAPY (PARAMOMYCIN OINTMENT, CRYOTHERAPY AND INTRALESIONAL GLUCANTIME) IN COMPARISON WITH INTRALESIONAL GLUCANTIME FOR THE TREATMENT OF ACUTE CUTANEOUS LEISHMANIASIS. IRANIAN JOURNAL OF DERMATOLOGY, [online] 3(3 (27)), pp.136-139. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=48109.



 
 
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