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Paper Information

Journal:   TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)   2003 , Volume 61 , Number 5; Page(s) 400 To 404.
 
Paper: 

THE EVALUATION OF 6 AND 12 HOUR URINE COLLECTION FOR ASSESSING PROTEINURIU IN THE HYPERTENSIVE GRAVIDA

 
 
Author(s):  RAHIMI SHERBAF MOGHADAS F.*, KHALILIAN S.
 
* 
 
Abstract: 

Background: The objective of this study was to determine wether a urine collection of less than 24 hours duration accurately assesses the level of preteinuria in inpatients being evaluated for preeclampsia.
Materials and Methods: Patients admitted to the Mirza Kouchak-Khan hospital between years 2001 to 2002, underwent 3 consecutive collections consisting of two b hour and one 12 hour collection. Each volume, and urine creatinine. A concurrent serum creatinine value was obtained. The protein: creatinine ratio and creative clearance were calculated. Pearsons correlation/sensitivity, specificity and positive and negative predictive values were assessed.
Results: A total of 32 patients (98%) were preeclamptic. Total protein and serum creatinine were significantly correlated and the protein: creatinine ratio was moderately correlated between the collections. The 1st 6 hours collection (
8 Am to 2 pm) had a sensitivity and specificity of 100%. The second 6 hours had a sensitivity and specificity of 96% and 86.6%. The first 12 hours had a sensitivity and specificity of 100% and 93.2%. The 2 and 12 hours (8 Am to 8 pm) had a sensitivity and specificity of 80% and 93.3% respectively. There was a significant diurnal pattern of proteinuria.
Conclusion: In conclusion based on the results achieved it can be concluded that a 6 and 12 hours urine collection/especially the first 6 hours after patient awakening can accurately assess proteinuria in the hypertensive gravida.

 
Keyword(s): PREECLAMPSIA, PROTEINURIA, DIAGNOSIS, 24-HOUR URINE, 12-HOUR URINE
 
References: 
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