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Paper Information

Journal:   IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES   Winter 2004 , Volume 6 , Number 4 (20); Page(s) 9 To 13.
 
Paper: 

ESTABLISHMENT AND BEHAVIORAL STUDY OF A TUMOR MODEL IN BALB/C MICE FOR EXPERIMENTAL CANCER STUDIES

 
 
Author(s):  BAHREYNI TOUSI SEYED MOHAMMAD HOSSEIN, SAZGARNIA A., MAHMOUDI M.
 
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Abstract: 

The establishment of a standard and well-studied animal tumor model in order to evaluate the effects of new anti-cancer therapeutics and the study of tumor biology is crucial to cancer research institutes in Iran. In this study, we established a standard tumor model in Balb/c mice. After the evaluation of the available cell lines, WEHI-164 cells were used for tUl110rinduction in male and female four-week inbred Balb/c mice.

On the day 0, mice were inoculated with 7 × 106 WEHI-164 cells subcutaneously and tumor dimensions were measured daily. Statistical analysis of the results indicated that there is no significant difference between male and female groups and the yield of 82% about tumor induction was determined. From the day 8, tumor regression was observed.

 

 

 

 
Keyword(s): IN VIVO, TUMOR MODEL, WEHI-164, BALB/C MICE
 
 
References: 
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Citations: 
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+ Click to Cite.
APA: Copy

BAHREYNI TOUSI, S., & SAZGARNIA, A., & MAHMOUDI, M. (2004). ESTABLISHMENT AND BEHAVIORAL STUDY OF A TUMOR MODEL IN BALB/C MICE FOR EXPERIMENTAL CANCER STUDIES. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 6(4 (20)), 9-13. https://www.sid.ir/en/journal/ViewPaper.aspx?id=46696



Vancouver: Copy

BAHREYNI TOUSI SEYED MOHAMMAD HOSSEIN, SAZGARNIA A., MAHMOUDI M.. ESTABLISHMENT AND BEHAVIORAL STUDY OF A TUMOR MODEL IN BALB/C MICE FOR EXPERIMENTAL CANCER STUDIES. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES. 2004 [cited 2021October17];6(4 (20)):9-13. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=46696



IEEE: Copy

BAHREYNI TOUSI, S., SAZGARNIA, A., MAHMOUDI, M., 2004. ESTABLISHMENT AND BEHAVIORAL STUDY OF A TUMOR MODEL IN BALB/C MICE FOR EXPERIMENTAL CANCER STUDIES. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, [online] 6(4 (20)), pp.9-13. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=46696.



 
 
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