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Paper Information

Journal:   INTERNATIONAL JOURNAL OF NANO DIMENSION (IJND)   SUMMER 2013 , Volume 4 , Number 1 (13); Page(s) 13 To 20.
 
Paper: 

TRACE DETERMINATION OF GATIFLOXACIN IN PHARMACEUTICAL AND BIOLOGICAL SAMPLES USING HYDROPHOBIC MAGNETIC NANOPARTICLES-ASSISTED IONIC LIQUID MICROEXTRACTION COUPLED WITH SPECTROFLUORIMETRY

 
 
Author(s):  MOTEVALLI K.*, YAGHOUBI Z.
 
* DEPARTMENT OF APPLIED CHEMISTRY, FUNDAMENTAL SCIENCES FACULTY, ISLAMIC AZAD UNIVERSITY, SOUTH TEHRAN BRANCH, TEHRAN, IRAN
 
Abstract: 

A simple and rapid microextraction procedure based on the application of magnetic nanoparticles and hydrophobic 1-Hexylpyridinium hexafluorophosphate [Hpy][PF6] ionic liquid (IL) was applied to trace determination of gatifloxacin. A mixture of [Hpy][PF6] and magnetic nanoparticles was injected into the sample solution containing the analyse of interest and a cloudy solution was formed. After centrifuging, the sediment phase containing enriched analyse was determined by spectrofluorimetry. Magnetic nanoparticles used in this microextraction procedure significantly improved the extraction recovery which is due to its proper hydrophobicity. [Hpy][PF6] was used as the extraction solvent due to some physicochemical properties such as high hydrophobicity, water immiscibility and quite viscosity. Under optimum experimental conditions, the proposed method provided a limit of detection (LOD) of 0.09 mg L-1 and a relative standard deviation (R.S.D.) of 3.0%. The present technique was applied to gatifloxacin determination in pharmaceutical formulations and human urine.

 
Keyword(s): IONIC LIQUID, MICROEXTRACTION, MAGNETIC NANOPARTICLES, GATIFLOXACIN, SPECTROFLUORIMETER, PHARMACEUTICAL
 
 
References: 
 
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APA: Copy

MOTEVALLI, K., & YAGHOUBI, Z. (2013). TRACE DETERMINATION OF GATIFLOXACIN IN PHARMACEUTICAL AND BIOLOGICAL SAMPLES USING HYDROPHOBIC MAGNETIC NANOPARTICLES-ASSISTED IONIC LIQUID MICROEXTRACTION COUPLED WITH SPECTROFLUORIMETRY. INTERNATIONAL JOURNAL OF NANO DIMENSION (IJND), 4(1 (13)), 13-20. https://www.sid.ir/en/journal/ViewPaper.aspx?id=363296



Vancouver: Copy

MOTEVALLI K., YAGHOUBI Z.. TRACE DETERMINATION OF GATIFLOXACIN IN PHARMACEUTICAL AND BIOLOGICAL SAMPLES USING HYDROPHOBIC MAGNETIC NANOPARTICLES-ASSISTED IONIC LIQUID MICROEXTRACTION COUPLED WITH SPECTROFLUORIMETRY. INTERNATIONAL JOURNAL OF NANO DIMENSION (IJND). 2013 [cited 2021October16];4(1 (13)):13-20. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=363296



IEEE: Copy

MOTEVALLI, K., YAGHOUBI, Z., 2013. TRACE DETERMINATION OF GATIFLOXACIN IN PHARMACEUTICAL AND BIOLOGICAL SAMPLES USING HYDROPHOBIC MAGNETIC NANOPARTICLES-ASSISTED IONIC LIQUID MICROEXTRACTION COUPLED WITH SPECTROFLUORIMETRY. INTERNATIONAL JOURNAL OF NANO DIMENSION (IJND), [online] 4(1 (13)), pp.13-20. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=363296.



 
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