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Paper Information

Journal:   THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES   Summer 2000 , Volume 11 , Number 2; Page(s) 101 To 106.
 
Paper: 

STUDY OF SERUM LEVELS OF APO-A1, AND APO-B IN PREGNANT WOMEN AND COMPARISION WITH CONTROL GROUP

 
 
Author(s):  ANSARI M.H., RAHIMIPOOR A., ABD ELAHIFARD S.
 
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Abstract: 

To study the events in pregnancy, such as Hypenension, unnatural hemorrhage, eclampsia and preeclampsia and to study in the relation between these events and serum levels of APOA1 and APOB, the serum levels of APOA1 and APOB were estimated in 45 pregnant women (with I out events) and in 35 pregnant women (with events) and in 35 healthy women in the same age group. Then these three groups were compared together in serum levels of APOA1 and APOB.
There was no significant increase in serum levels of APOA1 in the pregnant (without events), compared to pregnant (with events) and compared to control group (P>0.0.5).
In comparison with control group there was significant increase in the plasma levels of APOA1 in the pregnant (with events) (P<0.05).
In comparison with control group there was significant increase in the plasma levels of APOB in the pregnant (with and without events) (P<0.005).
But there was no significant increase in the plasma levels of APOB in the pregnant (with events) in comparison with pregnant (with out events) (P>0.05).
This study showed a positive correlation between APOA1 and APOB in pregnant (with and without events) and in control group, but this correlation was significant only in pregnant (with out events). These data suggest that the serum levels of APOA1 and APOB increase in normal pregnancy in comparison with control group and also increase in pregnant with events in comparison with pregnant without events (normal pregnant) and there is a positive correlation between events of pregnancy and serum levels of APOA1 and APOB.

 
Keyword(s): APOA1, APOB, PREGNANCY
 
References: 
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