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Paper Information

Journal:   INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY   JANUARY-MARCH 2013 , Volume 6 , Number 4; Page(s) 208 To 213.
 
Paper: 

ENDOTHELIAL PROGENITOR CELL DYSFUNCTION IN POLYCYSTIC OVARY SYNDROME: IMPLICATIONS FOR THE GENESIS OF CARDIOVASCULAR DISEASES

 
 
Author(s):  YU HSUN KAO, CHIU WAN CHUN, HSU MING I., CHEN YI JEN*
 
* DIVISION OF CARDIOVASCULAR MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, WAN FANG HOSPITAL, TAIPEI MEDICAL UNIVERSITY, TAIPEI, TAIWAN
 
Abstract: 
Polycystic ovary syndrome (PCOS), the most common endocrine disorder affecting women of reproductive age, is characterized by hyperandrogenism and insulin resistance. Women with PCOS have a higher risk for cardiovascular diseases (CVDs) and endothelial dysfunction. The mechanisms underlying these risks are unclear. Human peripheral blood contains circulating endothelial progenitor cells (EPCs) derived from bone marrow that have the ability to proliferate and differentiate into mature endothelial cells, which may contribute to vessel homeostasis and repair.
PCOS is associated with insulin resistance, hyperinsulinemia, and dyslipidemia, which may result in EPC dysfunction. In this review, we summarize the potential mechanisms of EPC dysfunction in PCOS, which possibly result in a higher genesis of CVDs in PCOS-affected subjects.
 
Keyword(s): POLYCYSTIC OVARY SYNDROME, PROGENITOR CELLS, CARDIOVASCULAR DISEASE, ENDOTHELIAL
 
 
References: 
 
Citations: 
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APA: Copy

YU HSUN, K., & CHIU WAN, C., & HSU, M., & CHEN, Y. (2013). ENDOTHELIAL PROGENITOR CELL DYSFUNCTION IN POLYCYSTIC OVARY SYNDROME: IMPLICATIONS FOR THE GENESIS OF CARDIOVASCULAR DISEASES. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 6(4), 208-213. https://www.sid.ir/en/journal/ViewPaper.aspx?id=286111



Vancouver: Copy

YU HSUN KAO, CHIU WAN CHUN, HSU MING I., CHEN YI JEN. ENDOTHELIAL PROGENITOR CELL DYSFUNCTION IN POLYCYSTIC OVARY SYNDROME: IMPLICATIONS FOR THE GENESIS OF CARDIOVASCULAR DISEASES. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY. 2013 [cited 2021October23];6(4):208-213. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=286111



IEEE: Copy

YU HSUN, K., CHIU WAN, C., HSU, M., CHEN, Y., 2013. ENDOTHELIAL PROGENITOR CELL DYSFUNCTION IN POLYCYSTIC OVARY SYNDROME: IMPLICATIONS FOR THE GENESIS OF CARDIOVASCULAR DISEASES. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, [online] 6(4), pp.208-213. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=286111.



 
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