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Journal:   PAJOUHESH DAR PEZESHKI   FALL 2010 , Volume 34 , Number 3; Page(s) 182 To 186.
 
Paper: 

Assessment Serum Lh, Fsh /Tumor Fluid Fsh, Lh Ratio In Ovarian Mass

 
 
Author(s):  Hosseini Maryam Al Sadat*, Masoumi Kashani Nadereh
 
* 
 
Abstract: 
Background: Regarding the prevalence and high mortality rate of ovarian cancers, importance of markers to determine ovarian malignancies earlier, considerable experimental evidence about serum Gonadotropins to cyst fluid ratio with pathology of ovarian tumors and finally not enough experiments in our country, the present study was performed in Imam Hossein hospital between 2008 and 2010.Methods: This study was cross-sectional and performed in patients operated because of ovarian mass. Their serum samples and cyst fluid obtained at the time of laparotomy and histopathologic diagnosis was established after removal of the tumor. FSH and LH concentration were measured in serum and tumor fluid based on Micro particle Enzyme Immunoassay technology in Imam Hossein laboratory. Ratios of them were determined in four pathologic groups (simple cyst, benign, borderline and malignant) and statistical comparison was done with the Kruskal-Wallis and Mann-Whitney U-test.Results: We studied 100 patients with ovarian mass but pathology of 79 patients was epithelial tumors and simple cysts. The most common mass were simple cysts (48.1%) and then benign tumors (27.8%), malignant tumors (16.5%) and borderline tumors (7.6%). Serum FSH / tumor fluid ratios were in simple cysts (21.1±53.8), benign tumors (50.7±174.9), borderline tumors (1.5±0.7) and malignant tumors (1.9±1.9) (P<0.001) and serum LH/tumor fluid ratios were in simple cysts (12.1±26.5), benign tumors (20.0±29.1), borderline tumors (2.6±2.3) and malignant tumors (2.8±3.7) (P<0.002).Conclusion: Our findings suggest that serum gonadotropins / tumor fluid ratio can be used as a tumor marker for identification of ovarian tumors. Also serum gonadotropins / tumor fluid ratio could be of value in differential diagnosis of ovarian tumors after determination normal and abnormal cut off point and ratios of them.
 
Keyword(s): OVARIAN EPITHELIAL TUMOR, SIMPLE CYST, GONADOTROPIN, OVARIAN TUMOR FLUID
 
 
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APA: Copy

HOSSEINI, M., & MASOUMI KASHANI, N. (2010). ASSESSMENT SERUM LH, FSH /TUMOR FLUID FSH, LH RATIO IN OVARIAN MASS. PAJOUHESH DAR PEZESHKI, 34(3), 182-186. https://www.sid.ir/en/journal/ViewPaper.aspx?id=259069



Vancouver: Copy

HOSSEINI MARYAM AL SADAT, MASOUMI KASHANI NADEREH. ASSESSMENT SERUM LH, FSH /TUMOR FLUID FSH, LH RATIO IN OVARIAN MASS. PAJOUHESH DAR PEZESHKI. 2010 [cited 2022August20];34(3):182-186. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=259069



IEEE: Copy

HOSSEINI, M., MASOUMI KASHANI, N., 2010. ASSESSMENT SERUM LH, FSH /TUMOR FLUID FSH, LH RATIO IN OVARIAN MASS. PAJOUHESH DAR PEZESHKI, [online] 34(3), pp.182-186. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=259069.



 
 
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