The aim of this study was to examine mediation effect of anger rumination on the relationship between dimensions of anger and anger control including trait anger, state anger, anger in, anger out, anger-control in, and anger-control out with physical health in a sample of Iranian general population. A total of 449 volunteers (332 men, 355 women) were included in this study. All participants were asked to complete the Tehran Multidimensional Anger Scale (TMAS), Anger Rumination Scale (ARS), and the Mental Health Inventory (MHI). Higher levels of anger was associated with lower levels of physical health as well as higher levels of physical illness. In contrast, higher levels of anger control was associated with higher levels of physical health as well as lower levels of physical illness. Analysis of the data revealed that anger rumination mediated the relationship between dimensions of anger and anger control with physical health in opposite directions. The mediating effect of anger rumination for the association of trait anger, state anger, anger-control in, and anger-control out with physical health was full, while mediation effect of anger rumination for the association of anger control dimensions with physical health was partial.