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Paper Information

Journal:   JOURNAL OF MEDICAL SCIENCE OF ISLAMIC AZAD UNIVERSITY OF MASHHAD   SUMMER 2009 , Volume 5 , Number 2 (18); Page(s) 85 To 90.
 
Paper: 

STUDYING THE INCREASE OF ACTIVITY LEVEL OF SERUM ALKALINE PHOSPHATASE IN CRYSTAL ADDICTS

 
 
Author(s):  AFSHARNEZHAD SIMA*, MAHMOODI MOHAMAD, ERFANIAN AHMAD POR MAHMOOD, JAMI ALAHMADI KHADIJE
 
* SHAHINFAR MEDICAL FACULTY, AZADI ST., MASHHAD, IRAN
 
Abstract: 

introduction: Crystal is one the pernicious addictive drugs which has unfortunately been imported to Iran in the recent years. As Crystal is the purified form of Heroin, its adverse effects are much more serious than those of Heroin. Apart from psychological effects, addiction to Crystal may have adverse effects on organs and tissues. So, the evaluation of enzymatic changes could be helpful in identifying the origin of damages. Alkaline phosphatase is present in most tissues and the most prevalent cause of its elevation is liver and bone diseases. Since liver damages may be caused by Heroin consumption, assaying ALP levels could be useful for investigating the adverse effects of this drug.
Materials and Methods: This study is a case control study which was carried out on 50 control persons and 108 crystal addicts who referred to Salehabad Center of Drug Addiction Treatment (Torbat jam) for the first time during 2008-2010. The activity level of Alkaline phosphatase in the serum was measured with Calorimetry-Spectrophotometry Using computer software SPSS-16, t-test was used to analyze the data.
Results: The results of this study indicate that there is a significant relationship between Crystal consumption and the serum level of ALP in both groups (P= 0.001). Besides, the relationships between the duration of Crystal consumption with Alkaline phosphatase level and cigarette smoking were significant.
Conclusion: Our results revealed that Crystal consumption is an important factor for elevating the ALP serum level in Crystal addicts.

 
Keyword(s): ALKALINE PHOSPHATASE, CRYSTAL, DURATION OF CRYSTAL CONSUMPTION, CIGARETTE SMOKING
 
 
References: 
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Citations: 
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APA: Copy

AFSHARNEZHAD, S., & MAHMOODI, M., & ERFANIAN AHMAD POR, M., & JAMI ALAHMADI, K. (2009). STUDYING THE INCREASE OF ACTIVITY LEVEL OF SERUM ALKALINE PHOSPHATASE IN CRYSTAL ADDICTS. JOURNAL OF MEDICAL SCIENCE OF ISLAMIC AZAD UNIVERSITY OF MASHHAD, 5(2 (18)), 85-90. https://www.sid.ir/en/journal/ViewPaper.aspx?id=204604



Vancouver: Copy

AFSHARNEZHAD SIMA, MAHMOODI MOHAMAD, ERFANIAN AHMAD POR MAHMOOD, JAMI ALAHMADI KHADIJE. STUDYING THE INCREASE OF ACTIVITY LEVEL OF SERUM ALKALINE PHOSPHATASE IN CRYSTAL ADDICTS. JOURNAL OF MEDICAL SCIENCE OF ISLAMIC AZAD UNIVERSITY OF MASHHAD. 2009 [cited 2021October28];5(2 (18)):85-90. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=204604



IEEE: Copy

AFSHARNEZHAD, S., MAHMOODI, M., ERFANIAN AHMAD POR, M., JAMI ALAHMADI, K., 2009. STUDYING THE INCREASE OF ACTIVITY LEVEL OF SERUM ALKALINE PHOSPHATASE IN CRYSTAL ADDICTS. JOURNAL OF MEDICAL SCIENCE OF ISLAMIC AZAD UNIVERSITY OF MASHHAD, [online] 5(2 (18)), pp.85-90. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=204604.



 
 
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