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Paper Information

Journal:   IRANIAN JOURNAL OF PSYCHIATRY AND CLINICAL PSYCHOLOGY   FALL 2010 , Volume 16 , Number 3 (62); Page(s) 366 To 366.
 
Paper: 

POST HUMAN GENOME ERA

 
 
Author(s):  GHAHREMANI H.*
 
* DEPARTMENT OF PHARMACOLOGY-TOXICOLOGY, FACULTY OF PHARMACY AND DEPARTMENT OF MOLECULAR MEDICINE, SCHOOL OF ADVANCE MEDICAL TECHNOLOGIES, TEHRAN UNIVERSITY OF MEDICAL SCIENCES (TUMS)
 
Abstract: 

The impact of genetics on human disorders in 80’s has changed the research as well as therapeutic approaches toward genetic characteristic and discovery of molecular basis of disease in 90’s. Molecular characteristics of less than 80 disorders have been identified up to 1990, while the research has revoked and in 1991 alone more than 83 disorders have been molecularly characterized. These findings engaged the scientific community to complete human genome sequence in 2001. However, the genome data failed to reveal all the functions as well as change in disease pathology. Thus, post-genome era started to explore the function, modification as well as alteration in transcription, metabolism and protein content on the course of disease progress. Therefore, transcriptomics, proteomics and metabolomics as well as functional genomics have been engaged to advance the knowledge on the genome-function relationship, protein function to shed light on the molecular basis of disease to target multifactor disordered for molecular treatments. The discovery of the causes of mental disorders to prevent and/or treat these disorders has been a long lasting labor intensive investigation. Since, the multiparametic nature of these disorders and lack of animal model render the pace of research. The spectacular increase in the amount of genomic information provides a remarkable impact on the way that medicine is practiced. Fortunately, with the information of human genome as well as post genome investigations, there are possibilities to identify the molecular basis of mental disorders and find a better therapeutic approach in the future.

 
Keyword(s): 
 
 
References: 
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Cite:
APA: Copy

GHAHREMANI, H. (2010). POST HUMAN GENOME ERA. IRANIAN JOURNAL OF PSYCHIATRY AND CLINICAL PSYCHOLOGY, 16(3 (62)), 366-366. https://www.sid.ir/en/journal/ViewPaper.aspx?id=194807



Vancouver: Copy

GHAHREMANI H.. POST HUMAN GENOME ERA. IRANIAN JOURNAL OF PSYCHIATRY AND CLINICAL PSYCHOLOGY. 2010 [cited 2021April20];16(3 (62)):366-366. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=194807



IEEE: Copy

GHAHREMANI, H., 2010. POST HUMAN GENOME ERA. IRANIAN JOURNAL OF PSYCHIATRY AND CLINICAL PSYCHOLOGY, [online] 16(3 (62)), pp.366-366. Available: <https://www.sid.ir/en/journal/ViewPaper.aspx?id=194807>.



 
 
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