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Paper Information

Journal:   IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM)   NOVEMBER 2010 , Volume 12 , Number 4 (SN 52); Page(s) 352 To 358.
 
Paper: 

The Identification Of Related Risk Factors Of Thyroid Disorder In An Iranian Pregnant Population

 
 
Author(s):  Dehghani Zahedani M., Azinfar Azadeh, Mahouri Kh.*, Soulati S.M.
 
* HORMOZGAN FERTILITY AND INFERTILITY RESEARCH CENTER, BANDAR ABBAS, I.R. IRAN
 
Abstract: 
Introduction: The study aimed at determining the prevalence of thyroid disorders among a pregnant population and identifying the related risk factors of thyroid dysfunction in these subjects. Materials and Methods: Between February and July 2008, a nested case-control study was conducted on 608 pregnant women in Bandar Abbas, Iran. We obtained information about thyroid dysfunction in the subject and their family, diabetes mellitus type 1, prior gestational diabetes, hepatitis B and rubella vaccination, any previous miscarriages and fifteen symptoms of hypothyroidism. T4, T3, T3RU, FTI, TPO Abs were measured and thyroid examinations were carried out. Multiple logistic regression tests were used to estimate relative risk of thyroid dysfunction for the variables. The rate of hypothyroidism was compared in groups with significant related risk factors at high or lower risk. Results: Of the 608 pregnant women, 519(85.4%) were euthyroid, 72(11.8%) had sub clinical hypothyroidism, 3(0.5%) overt hypothyroidism and 14(2.3%) were hyperthyroid. There were strong correlations between personal history of thyroid dysfunction (OR:5.23 %95CI:2.11-12.95 P: 0.00), TPO Abs(OR:2.81 CI%95:1.83-4.32 P:0.00), 3 symptoms or more of hypothyroidism(OR:2.50 CI%95:1.48-4.22 P:0.001), goiter (OR:2.24 CI%95: 1.32-3.80 P:0.002), being in the 20-30 year age range (OR:1.87 %95CI:1.004-3.51 P:0.04) and being hypothyroid in pregnancy, respectively, but not with other risk factors, especially family history of thyroid disorder. Conclusion: This study showed thyroid disorders are common among pregnant population and are correlated with personal history of thyroid disorder, TPO Abs, 3 symptoms or more of hypothyroidism, goiter and age range between 20 to 30 years old, all risk factors which should be considered at screening, in clinical practice.
 
Keyword(s): THYROID, SUBCLINICAL HYPOTHYROIDISM, PREGNANCY, THYROID FUNCTION TESTS
 
 
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APA: Copy

DEHGHANI ZAHEDANI, M., & AZINFAR, A., & MAHOURI, K., & SOULATI, S. (2010). THE IDENTIFICATION OF RELATED RISK FACTORS OF THYROID DISORDER IN AN IRANIAN PREGNANT POPULATION. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), 12(4 (SN 52)), 352-358. https://www.sid.ir/en/journal/ViewPaper.aspx?id=184162



Vancouver: Copy

DEHGHANI ZAHEDANI M., AZINFAR AZADEH, MAHOURI KH., SOULATI S.M.. THE IDENTIFICATION OF RELATED RISK FACTORS OF THYROID DISORDER IN AN IRANIAN PREGNANT POPULATION. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM). 2010 [cited 2022January19];12(4 (SN 52)):352-358. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=184162



IEEE: Copy

DEHGHANI ZAHEDANI, M., AZINFAR, A., MAHOURI, K., SOULATI, S., 2010. THE IDENTIFICATION OF RELATED RISK FACTORS OF THYROID DISORDER IN AN IRANIAN PREGNANT POPULATION. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), [online] 12(4 (SN 52)), pp.352-358. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=184162.



 
 
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