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Paper Information

Journal:   TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)   2004 , Volume 62 , Number 7; Page(s) 541 To 550.
 
Paper: 

VALUE OF INJECTION SITE IN ASSESSING OPIOD TOXICITY BY THIN LAYER CHROMATOGRAPHY

 
 
Author(s):  BAROONI S., VAHHABI ANARAKI M.R., TARREMIAN F.
 
* 
 
Abstract: 

Background: Detection of poisons as a postmortem finding has to diagnostic importance in forensic pathology. Using of tissues those need minimal handling of corpse is a goal. Opioid toxicity is the most common cause of poisoning in corpses those referred autopsy. So we decided to conduct a research on the site of injection as a valuable analytical tissue.
Materials and Methods: In this study 54 corpses who returned to autopsy room at Legal Medicine Organization (LMO) during year 1380 with addiction to opioid were investigated. The latest injection side determined in each case. Cases with pre-mortem hospital admission, post- mortem putrification and signs of bums as any cases of death other than opioid injection were not included with study. In addition to used external examinations and autopsy the blood, urine, visceral and injection site tissues specimen were separately packed in standard containers, sent to Toxicological laboratory in that Organization.
Results: The results of studies as samples with Thin Layer Chromatography (TLC) were achieved as follows: In toxicological exams on urine, blood, and visceral specimens, 47 cases (87%) yielded definitely at least one opioid positive result with 7 cases opioid negative results in all investigated specimens. No opioid positive result was achieved from injection result

Was achived from injection sites samples of all cases.

Conclusion: Conclusively this study mentions that laboratory examination on venous injection site with TLC to determine opioid injection is insensitive.

 
Keyword(s): FORENSIC TOXICOLOGY, HEROIN, NARCOTICS, INJECTION SITE, BLOOD, AUTOPSY, ADDICTION
 
References: 
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