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Paper Information

Journal:   JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE   FALL 2007 , Volume 25 , Number 3 (73); Page(s) 283 To 289.
 
Paper: 

RELATION BETWEEN SALIVARY ASPARTATE AMINOTRANSFARASE AND PERIODONTAL DISEASE

 
 
Author(s):  GHASEMI MAHMOUD*, BABAEI AZADEH
 
* DEPT. OF PERIODONTICS, DENTAL SCHOOL, ISLAMIC AZAD UNIVERSITY, TEHRAN, IRAN
 
Abstract: 

Background & Aim: The previous studies demonstrated that there is a strong relationship between the levels of Aspartate aminotransferase (AST) and the progression of the periodontal disease. The aim of this study was to evaluate the level of this enzyme in various stage of the periodontal disease.
Methods & Materials: Sixty volunteers participated in this historical cohort study. They were divided in three groups of 20 each; group 1 (healthy periodontium), group 2 (early periodontitis), and group 3 (advanced periodontitis).
Following periodontal examination including plaque index, bleeding on probing, pocket depth, and attachment level, 1ml of unstimulated saliva was collected and evaluated for the differences by means of Kruskal Wallis and student t tests.
Result: There was a higher level of the enzyme in the saliva of the subjects with advanced periodontitis (67.95 16.4) compared to periodontally normal (36.8 13.5) and early periodontitis (43.45 18.4) patients, and the difference was highly significant (P<0.0001).
Conclusion: There seems to be a positive relationship between periodontal disease severity and the higher value of the AST enzyme in saliva. The results should be confirmed by longitudinal studies evaluating the various parameters of the periodontal disease.

 
Keyword(s): SALIVA, PERIODONTITIS, ASPARTATE AMINOTRANSFERASE, ATTACHMENT LOSS
 
References: 
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