Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   IRANIAN JOURNAL OF PUBLIC HEALTH   2007 , Volume 36 , Number 4; Page(s) 1 To 5.
 
Paper: 

Diversity Of Merozoite Surface Protein-3Beta Gene Of Plasmodium Vivax Isolates From Iran

 
 
Author(s):  Shahbazi A., Raeisi A., Nateghpour M.*, Mirhendi H., Mohebali M., Asmar M.
 
* DEPT. OF MEDICAL PARASITOLOGY AND MYCOLOGY, SCHOOL OF PUBLIC HEALTH, MEDICAL SCIENCES/UNIVERSITY OF TEHRAN, IRAN
 
Abstract: 
Background: Plasmodium vivax malaria accounts for approximately 88% of malaria cases in Iran. There is limited information on genetic diversity of P. vivax in the country and a need to develop and apply an effective vaccine against the disease is necessary. Among many potential candidates, MSP -3b gene is promising target. This study was designed and carried out to determine the variation of this gene as genetic marker in population of malarious areas of Iran. Methods: Blood sample of 85 P. vivax isolates from four southern and east-southern provinces of the country assessed for polymorphism of PvMSP-3b gene by PCR/RFLP method. Results: Based on the size of PCR product of the gene, 7 genetically different types of parasite has been distinguished. Two alleles were simultaneously visible in 19 % of the cases. Results from PCR/RFLP analysis of PvMSP-3b gene showed at least 15 allelic groups. Multiple infections have been found in 2.4 % of the cases. Conclusion: PvMSP-3b gene was highly diverse in P. vivax isolates of malarious areas of Iran, and can be a suitable marker for population genetic studies of P. vivax. More investigations on PvMSP-3b genes are needed to reveal genetic structure of P. vivax in Iran.
 
Keyword(s): PLASMODIUM VIVAX, PVMSP-3BETA, PCR/RFLP, IRAN
 
 
International related papers: 
 
Most related Highly related Moderately related Least related
 
References: 
  • Not Registered.
  •  
  •  
 
Citations: 
 
+ Click to Cite.
APA: Copy

SHAHBAZI, A., & RAEISI, A., & NATEGHPOUR, M., & MIRHENDI, H., & MOHEBALI, M., & ASMAR, M. (2007). DIVERSITY OF MEROZOITE SURFACE PROTEIN-3BETA GENE OF PLASMODIUM VIVAX ISOLATES FROM IRAN. IRANIAN JOURNAL OF PUBLIC HEALTH, 36(4), 1-5. https://www.sid.ir/en/journal/ViewPaper.aspx?id=100262



Vancouver: Copy

SHAHBAZI A., RAEISI A., NATEGHPOUR M., MIRHENDI H., MOHEBALI M., ASMAR M.. DIVERSITY OF MEROZOITE SURFACE PROTEIN-3BETA GENE OF PLASMODIUM VIVAX ISOLATES FROM IRAN. IRANIAN JOURNAL OF PUBLIC HEALTH. 2007 [cited 2022January20];36(4):1-5. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=100262



IEEE: Copy

SHAHBAZI, A., RAEISI, A., NATEGHPOUR, M., MIRHENDI, H., MOHEBALI, M., ASMAR, M., 2007. DIVERSITY OF MEROZOITE SURFACE PROTEIN-3BETA GENE OF PLASMODIUM VIVAX ISOLATES FROM IRAN. IRANIAN JOURNAL OF PUBLIC HEALTH, [online] 36(4), pp.1-5. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=100262.



 
  pdf-File
Yearly Visit 48
 
 
Latest on Blog
Enter SID Blog