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Journal:   IRANIAN JOURNAL OF VETERINARY RESEARCH (IJVR)   2008 , Volume 9 , Number 2 (23); Page(s) 150 To 157.
 
Paper: 

Experimental Infection Of Stray Cats With Human Isolates Of Helicobacter Pylori

 
 
Author(s):  Khoushnegah J., Jamshidi Shahram*, Mohammadi M., Shojaei Tabrizi A., Mohajerani N., Zahraei Salehi M.T.
 
* DEPARTMENT OF CLINICAL SCIENCES, FACULTY OF VETERINARY MEDICINE, UNIVERSITY OF TEHRAN, TEHRAN, IRAN
 
Abstract: 
To improve our understanding of Helicobacter infection in cats and to determine whether they are reservoirs for H. pylori and sources of zoonotic transmission to humans, we selected cats as an experimental animal model for gastric colonization by H. pylori. Sixteen stray cats underwent Helicobacter eradication treatment followed by three consecutive oral inoculations of a cocktail of human H. pylori isolates. Four out of sixteen inoculated cats became colonized by H. pylori as confirmed by genus- and species-specific PCR. In conclusion, human H. pylori isolates are able to colonize the stomach of cats. It seems that the stray cat can be used as an experimental model in the future investigations of H. pylori-induced pathogenesis as well as evaluation of anti-H. pylori prevention and treatment regimens. Further experimental studies using more animals are needed to identify the usefulness of the cat as an experimental model.
 
Keyword(s): H. PYLORI, COLONIZATION, PCR, CAT
 
 
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APA: Copy

KHOUSHNEGAH, J., & JAMSHIDI, S., & MOHAMMADI, M., & SHOJAEI TABRIZI, A., & MOHAJERANI, N., & ZAHRAEI SALEHI, M. (2008). EXPERIMENTAL INFECTION OF STRAY CATS WITH HUMAN ISOLATES OF HELICOBACTER PYLORI. IRANIAN JOURNAL OF VETERINARY RESEARCH (IJVR), 9(2 (23)), 150-157. https://www.sid.ir/en/journal/ViewPaper.aspx?id=109567



Vancouver: Copy

KHOUSHNEGAH J., JAMSHIDI SHAHRAM, MOHAMMADI M., SHOJAEI TABRIZI A., MOHAJERANI N., ZAHRAEI SALEHI M.T.. EXPERIMENTAL INFECTION OF STRAY CATS WITH HUMAN ISOLATES OF HELICOBACTER PYLORI. IRANIAN JOURNAL OF VETERINARY RESEARCH (IJVR). 2008 [cited 2022August12];9(2 (23)):150-157. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=109567



IEEE: Copy

KHOUSHNEGAH, J., JAMSHIDI, S., MOHAMMADI, M., SHOJAEI TABRIZI, A., MOHAJERANI, N., ZAHRAEI SALEHI, M., 2008. EXPERIMENTAL INFECTION OF STRAY CATS WITH HUMAN ISOLATES OF HELICOBACTER PYLORI. IRANIAN JOURNAL OF VETERINARY RESEARCH (IJVR), [online] 9(2 (23)), pp.150-157. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=109567.



 
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