In the present research the effects of high voltage current on open full thickness wound of rats from histological and biomechanical and wound contrition point of views were studied.
60 male rats were divided randomly into experimental and control groups.
Under general anesthesia with steril conditions one wound were made on the dorsum skin of neck of each rat. Features of high voltage current were 100 volts and 64 HZ and one hour per day. Polarity was negative for first 3 days and was positive for following days. At the fourth, seventh, and fifteenth day after surgery samples for histological and biomechanical study were obtained from wound tissue and adjacent tissue normal skin. Samples were prepared for light microscopic study and were stained with hematoxyline and eosin. Slides were studied by special eyepiece and fibroblast and macrophage and neutrophil and vessels counted and depth of wound tissue and thickness of new epiderm were calculated. Samples for biomechanical study were 15mm/min. Data were anlysed with Mann Whitney U test.
Results or experimental group were better for fourth day and of control group were better for seventh and fifteenth days.
Application of high voltage current were positive for inflammation phase of wound healing and were negative for proliferation and remodeling phase.