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Paper Information

Journal:   INTERNATIONAL JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE   JULY 2018 , Volume 9 , Number 3; Page(s) 113 To 119.
 
Paper: 

MERCURY-INDUCED OXIDATIVE STRESS MAY ADVERSELY AFFECT PREGNANCY OUTCOME AMONG DENTAL STAFF: A COHORT STUDY

 
DOI: 

10.15171/ijoem.2018.1181

 
Author(s):  EL BADRY AZIZA*, REZK MOHAMED, EL SAYED HANAN
 
* 25 YASIN ABDELGHAFAR ST, SHIBIN EL-KOM CITY, MENOUFIA GOVERNORATE, EGYPT
 
Abstract: 

Background: Dental staff may be at increased risk of adverse pregnancy outcome secondary to their chronic exposure to mercury.
Objective: To investigate obstetric outcome among dental staff and explore the oxidative stress induced by mercury exposure.
Methods: A cohort of 64 pregnant dental staff (exposed group) and 60 pregnant employees (non-exposed group) were studied. Urinary mercury level and blood antioxidant activity were measured. Participants were followed to assess their obstetric outcome.
Results: The exposed group had a higher mean urinary mercury level and a lower blood antioxidant activity during the three trimesters compared to non-exposed group (p<0.001). Women in the exposed group were experienced more frequently spontaneous abortion and pre-eclampsia (p<0.05). Babies born to the women in the exposed group tended to be smaller for gestational age compared to those of non-exposed group (p<0.001).
Conclusion: Pregnant dental staff suffered higher odds of developing spontaneous abortion and pre-eclampsia and giving birth to babies smaller for gestational age. This may be linked to oxidative stress induced by exposure to mercury.

 
Keyword(s): DENTAL STAFF, PREGNANCY OUTCOME, MERCURY POISONING, OXIDATIVE STRESS, ANTIOXIDANTS, GLUTATHIONE PEROXIDASE, SUPEROXIDE DISMUTASE
 
References: 
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