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Paper Information

Journal:   JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE   2006 , Volume 28 , Number 53; Page(s) 23 To 30.
 
Paper: 

COMPARISON OF ANALGESIC EFFECTS OF INTRAVENOUS SUFENTANIL AND INTRAARTICULAR INJECTION OF SUFENTANIL AND SUFENTANIL PLUS METHYLPREDINISOLONE AFTER ARTHROSCOPIC KNEE SURGERY

 
 
Author(s):  MOOSAVI TEKYE S.M., SHARIFIAN ATAR ALI REZA, AGHAEE R.
 
* 
 
Abstract: 

Background: Many different methods have been used in an effort to provide adequate analgesia after knee surgery. We chose sufentanil because of its greater lipophilic characteristics, which should provide a faster onset of analgesia than morphine.
Material and Methods: In a double blind randomized study,96 ASA physical status 1-11 patients ranging 20-45 years undergoing knee arthroscopic meniscec tomy were studeid. Patients were allocated to 3 groups receiving IV sufentanil, intraarticular sufen- tanil 10µg, or sufentanil 10µg plus methylpredni- solone 40mg at the end of arthroscopy during general anesthesia. Postoperatively, pain levels at rest and during movement (i.e., active flexion of the knee) were measured by a visual analogue scale. Supplementary analgesia - acetaminophen codein orally - was given at patient request. Statistical analysis was performed by the Mann-Whitney, U-test, Wilcoxon's test and the X2 test as appropriate. All data are presented as mean ±SD.
Results: With regard to demographic data, duration of anesthesia and tourniquet time, significant difference were not observed among groups A, Band C. Postoperatively, pain score during rest and movement were significantly higher in the IV group than in the other groups (p<0.05) and the difference between the Band C groups were also significant (p<0.05). Postopera- tively, supplementary analgesic consumption was significantly decreased in the intraartcular sufentanil and sufentanil plus methylprednisolone groups (p<0.05), and the difference between the Band C groups were also significant (p<0.05).
Conclusion: Intraarticular administration of sufentanil alone and combination of sufentanil and methylpred-nisolone after knee menisectomy are effective, reliable, and well tolerated analgesic techniques. Sufentanil plus methyl prednisolone reduced pain and use of supplementary analgesics effectively.

 
Keyword(s): SUFENTANIL, METHYL PREDNISOLONE, INTRAARTICULAR INJECTION, KNEE ARTHROSCOPY
 
References: 
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