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Paper Information

Journal:   OFOGH-E-DANESH   Winter 2005 , Volume 10 , Number 4; Page(s) 23 To 27.
 
Paper: 

DETERMINATION OF TOTAL IGE AND EOSINOPHILS IN PEDIATRIC ASTHMATIC PATIENTS AGE 1 TO 12 YEARS OLD

 
 
Author(s):  HASHEMZADEH A., HEYDARIAN FARHAD, HASHEMZADEH S.
 
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Abstract: 

Background and Aim: Asthma is the most common cause of pediatric admission. Its incidence is 7.4%. Since this disorder is due to type one hyper sensitivity reaction related to IgE, this study focused on the relationship between total lgE and eosinophils in pediatric asthmatic patients.
Materials and Methods: This study was performed on asthmatic patients age 1-12 years old who admitted in hospital during one year. Diagnosis was made based on questionnaire, clinical findings including personal history and radiological findings. After selection of patients, the questionnaire was filled and data was analyzed based on t student and Mann- Whitney tests.
Results: The most common physical sign was wheezing (98.6%) and tachypnea was the next one (96.1 %) The average of total serum IgE was (175.8±198.6) and blood eosinophils was (403.1±300) There was a significant relation between total serum IgE and blood eosinophils (p: 0.01, r: 0.32) According to our findings the level of total serum IgE was above the normal limit in all age groups.
Conclusion: The level of total serum IgE and blood eosinophils, in pediatric asthmatic cases were above normal range, since there is an increase in total serum IgE in critical asthmatics, and it can be a predictive factor for severity of asthma.

 

 
Keyword(s): ASTHMA, IGE, WHEEZING, EOSINPHILIA
 
References: 
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