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Paper Information

Journal:   MODARES JOURNAL OF MEDICAL SCIENCES (PATHOBIOLOGY)   Spring-Summer 2005 , Volume 8 , Number 1; Page(s) 13 To 18.
 
Paper: 

A STUDY ON THE CLINICAL SYMPTOMS, EOSINOPHIL AND SERUM IMMUNOGLOBULIN ALTERATIONS IN THE PATIENTS INFECTED WITH GIARDIA LAMBLIA

 
 
Author(s):  DOLATYAR A.R.*, DALIMI ASL H.
 
* Department of Parasitology, Tarbiat Modares University, Tehran, Iran
 
Abstract: 

Purpose: In the present work, clinical symptoms, serum immunoglobulin alteration and eosinophil count were investigated in the patients infected with Giardia lamblia.

Materials and Methods: In this regard, 50 persons infected with Giardia and 50 healthy individuals were selected as the study and control groups respectively in Tehran. Sera of the groups were tested for IgG, IgE, IgA levels and their blood for the percentage of eosinophil. To measure IgA and IgG levels the SRID technique and to measure IgE level the ELISA technique were applied.

Results: Results indicated that, 78%, 74%, 60%, 58% and 12% of the patients showed diarrhea, abdominal pain, weight loss, flatulence and visual disorder respectively, while no aforementioned symptoms were observed in non-infected individuals. In addition, the mean of eosinophil percentage as well as IgA, IgG and IgE levels in the infected group were found to be higher than that of the non infected group significantly (P<0.05). Meanwhile, no elevation was observed in the eosinophil percentage or immunoglobulin levels of the control group.

Conclusion: In conclusion, Giardia lamblia can induce eosinophila and increase the level of IgE in the infected patients significantly.

 
Keyword(s): GIARDIA LAMBLIA, CLINICAL SYMPTOMS, EOSINOPHIL, SERUM IMMUNOGLOBULIN
 
References: 
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