Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES   Winter 2002 , Volume - , Number 20; Page(s) 24 To 29.
 
Paper: 

COMPARISON OF BETADINE SOLUTION AND ERYTHROMYCIN OINTMENT IN PROPHYLAXIS OF OPHTALMIA NEONATARUM

 
 
Author(s):  AGHADOUST D., SHARIF M.R., KHOURSHIDI A., MOUSAVI SEYED GHOLAM ABAS
 
* 
 
Abstract: 

Background: Neonatal conjunctivitis (ophtalmia Neonatarum) continues to cause blindness due to the unusefulness of agents used prophylactically in preventing this condition. Prepared povidone-iodine ophtalmic solution is an effective antibacterial and antiviral agent.

Objective: To evaluate and compare betadine solution 1% and erythromycin ointment

0.5% in prophylaxis of ophtalmia neonatarum.

Methods: Through a masked and prospective clinical trail, 300 infants born in Shahid Khani hospital of Kashan were studied. About 30 minutes after birth, 100 newborns received betadine solution 1% (group I), 100 newborns received 1 cm erythromycin rye ointment 0.5% (group II) and 100 newborns received no treatment (group Ill). All neonates were followed up for one month.

Findings: Rate of neonatal conjunctivitis was 9%, 12% and 34% in group I, II, III respectively (P<0.000l).No ocular side-effect of medications was seen in groups I and II.
Conclusion: Ophtalmic solution of betadine (1%) as a prophylaxis against ophthalmic neonatarum is more effective than treatment with erythromycin ointment 0.5% or without treatment. Additionally, it has wider spectrum and less cost and no or minimal ocular toxicity.

 

 

 

 
Keyword(s): BETADINE, ERYTHROMYCIN, OPHTALMIA NEONATARUM
 
References: 
  • ندارد
 
  Yearly Visit 79
 
Latest on Blog
Enter SID Blog