Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   KOOMESH   Winter 2001 , Volume 2 , Number 2; Page(s) 105 To 110.
 
Paper: 

EFFECT OF LOW MOLECULAR WEIGHT HEPARIN ON POST OPERATIVE INFLAMMATION IN PHACOMORPHIC GLAUCOMA

 
 
Author(s):  ABD ELAHI A.*, NAINI M.T.
 
* Farabi Hospital. Tehran Univeristy of Medical Sciences, Tehran, Iran
 
Abstract: 

Introduction: The aim of this study was to evaluate the effect of intraoperative low molecular weight (LMW) heparin in reducing the severity of postoperative inflammatory response after standard extracapsular cataract extraction and PCIOL implantation in cases of phacomorphic glaucoma.

Material and Method: In this randomized blind clinical trial 46 eyes (23 cases and 24 controls) were operated on by a single surgeon. In the cases, 5 IU/ml LMW heparin (Fragmin) was added to irrigating fluid. Intraoperative and postoperative hemorrhage, degree of postoperative fibrin and postoperative synechinae formation, pigment deposits on the intraocular lens were evaluated in the both cases and controls.

Results: Mean age was 68±8.1years. Male to female ratio was 1/2. Cases and controls were matched regarding age, sex, duration of operation and hospitalization, preoperative IOP, concurrent ocular or systemic disease and smoking. In the cases, there were significantly less cells, flare, fibrin, pigment deposits and inflammation. Final visual acuity was significantly (P< 0.001) better in case than control group (20/50 Vs 201125). Case and control groups were comparable regarding intraoperative and postoperative hemorrhage.

Conclusion: the data indicate that adding 5 IU/ml LMW heparin to the irrigating tluid during cataract surgery is safe, reduces postoperative fibrin formation and leads to better visual results in phacomorphic glaucoma.

 

 

 
Keyword(s): PHACOMORPHIC GLAUCOMA, HEPARIN, LOW MOLECULAR WEIGHT
 
References: 
  • ندارد
 
  Persian Abstract Yearly Visit 71
 
Latest on Blog
Enter SID Blog