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Paper Information

Journal:   IRANIAN JOURNAL OF MEDICAL SCIENCES (IJMS)   June 2006 , Volume 31 , Number 2; Page(s) 100 To 102.
 
Paper: 

EFFECT OF CUTANEOUS APPLICATION OF SUNFLOWER-SEED OIL ON SERUM TRIGLYCERIDE AND CHOLESTEROL LEVELS IN PRETERM INFANTS

 
 
Author(s):  POUR ARIAN SH.*, MADANI AHMAD, MOHAMMADI K.
 
* Neonatal Division, NICU, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
 
Abstract: 

Intravenous lipid solution (intralipid) provides essential substances for optimizing growth in premature infants, but has potential side effects. We investigated the effects of dermal application of sunflower-seed oil (SFSO) as a substitute for intralipid in preterm infants. This study comprised of 20 preterm infants, unable to be fed enterally divided into case and control groups of equal numbers. SFSO was rubbed over the whole skin (1 gr/kg, three times daily) in case group only. Serum triglyceride and cholesterol levels were measured in both groups initially, and on the third and seventh day. The initial mean of serum triglyceride (TG) levels in the case and control groups were 42.6±15.5mg/dl and 45.2±14.0 mg/dl respectively. TG level had a steady state increase at three (47%) and seven (80%) days of cutaneous application of SFSO in the case group, whereas, it decreased steadily in the control group. The respective initial mean cholesterol  levels in the study and control groups were 94.6 and 102.5 mg/dl which did not significantly change during the course of the study in both groups. This study is indicating that although, deficiency of essential fatty acids or their related clinical complications were not observed in either group, application of SFSO steadily improved the level of triglyceride in preterm infants. Therefore, dermal application of sunflower-seed oil is a noninvasive and economic way, and it appears to be a suitable non-complicated alternative for intralipid.

 

 

 
Keyword(s): PREMATURE INFANT, SUNFLOWER-SEED-OIL, INTRALIPID, HYPERALIMENTATION
 
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