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Paper Information

Journal:   ASIA OCEANIA JOURNAL OF NUCLEAR MEDICINE AND BIOLOGY   NOVEMBER 2014 , Volume 2 , Number SUPPLEMENT 1; Page(s) 31 To 31.
 
Paper: 

CHOLANGIOCARCINOMA WITH METASTASES TO BREAST: RARER THAN THE RARE ENTITY

 
 
Author(s):  AGARWAL VISHAL*
 
* MEDANTA THE MEDICITY HOSPITAL, INDIA
 
Abstract: 

Background: With over 1 million new cases in the world each year, breast cancer is the most common malignancy in women, and accounts for 18% of all female cancers. However, metastatic involvement of the breast is relatively rare, most common causes being contralateral breast cancer, malignant melanoma, lymphoma and lung cancer. Autopsy reports indicate an incidence of 1.7% to 6.6% for nonprimary breast malignancy.
Case: We present a young female of age 35 years with a liver mass and altered liver function tests. On FDG PET-
CT examination, FDG avid heterogeneously enhancing irregular lesion was noted in the right breast with another FDG avid peripherally enhancing rounded lesion in the left breast. Liver showed a peripherally enhancing FDG avid SOL in segment V, VIII and IV, with ill-defined margins and irregular peripheral enhancement & lobular outline.
Results: In view of hypermetabolic heterogeneously enhancing lesions in B/L breasts and FDG avid peripherally enhancing SOL in liver, diagnoses of metastatic Ca. breast was suggested and pathologic correlation was advised. However, HPE of right breast lesion confirmed it to be metastatic carcinoma rather than the primary of breast.
Conclusion: Cholangiocarcinoma is a slow growing rare, malignant tumor of the bile duct, accounting for less than 1% of all cancers. Mostly, it spreads locally via the lymphatics to regional lymphnodes. Metastatic focus in the breast is a very rare presentation, this being probably the first reported case.

 
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