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Paper Information

Journal:   INTERNATIONAL JOURNAL OF HETEROCYCLIC CHEMISTRY   SPRING 2012 , Volume 2 , Number 1; Page(s) 9 To 11.
 
Paper: 

SYNTHESIS OF ALKYL 2-(4-OXOQUINAZOLIN-3(4H)-YL) ACRYLATE BY NUCLEOPHILIC ADDITIONOF ALKYL PROPIOLATES CATALYSED BY PH3P

 
 
Author(s):  BABAKESHIZADEH MEHDI*, MOHTAT BITA
 
* DEPARTMENT OF ORGANIC CHEMISTRY, KARAJ BRANCH, ISLAMIC AZAD UNIVERSITY, KARAJ, IRAN
 
Abstract: 

4-Hydroxyquinazoline undergoes neutral conditions with alkyl propiolates in the presence of triphenylphosphine (0.26g), and by α substituation the corresponding 2-(4-oxoquinazolin-3(4H)-yl acrylate was obtained in good yields.

 
Keyword(s): 4-HYDROXYQUINAZOLINE, ALKYLACRYLAT, ALKYL PROPIOLATES, TRIPHENYLPHOSPHINE
 
References: 
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