Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   PAJOUHESH DAR PEZESHKI   Summer 2005 , Volume 29 , Number 2; Page(s) 157 To 164.
 
Paper: 

A SURVEY OF CONSUMPTION PATTERN OF ANTIBIOTICS IN TALEGHANI HOSPITAL

 
 
Author(s):  HAJEBI G., MORTAZAI S.A., GOUDARZI J.
 
* 
 
Abstract: 

Background: Irrational use of antibiotics, particularly their uncontrolled use, has led to an increase in the resistance of bacterial species, especially in hospital infections and also caused the emergence of hazardous side effects, albeit avoidable. This results in financial and clinical damages on the health system, some of which are irreparable.
Materials and methods: This study was carried out to determine the consumption pattern of antibiotics as per separate disease in the Taleghani Hospital in Tehran, between July and December 2001 based on the International Standard System, ATC/DDD, which is recommended by WHO, within the frame of DUE retrospective studies.
Results: During the study period, 2137 cases were investigated, among which 57% (1222 cases) had received antibiotics. The cost of these antibiotics amounted to 19.4% of the total drug expenses of the hospital. Of all the antibiotic-treated cases more than 68% had undergone surgery, among whom 49.9% (elective surgeries) received prophylactic antibiotics. The total amount of antibiotics was 99.8 DDD/100 bed days, 79.3% was in parenteral forms. Orthopedic and reconstructive surgery cases received the greatest amount of antibiotic consumption (23%). The most commonly used antibiotics were cephalosporins (49%) and penicillins (27%) followed by aminoglycosides (6%), imidazole derivatives (5%), and fluoroquinolones (4%).
Conclusion: Our results are in agreement with other similar Iranian studies; however, it differed significantly from European studies. The use of prophylactic antibiotic preoperatively on a few days basis (especially in elective surgeries), deems to be irrational. This is because reliable sources have highly recommended a reduction in dosage administration to less than 24 hours.

 
Keyword(s): ANTIBIOTIC, CONSUMPTION PATTERN, DEFINED DAILY DOSE
 
References: 
  • ندارد
 
  Persian Abstract Yearly Visit 83
 
Latest on Blog
Enter SID Blog