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Paper Information

Journal:   JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)   FEBRUARY 2014 , Volume 18 , Number 2; Page(s) 190 To 192.
 
Paper: 

HUMAN HERPES VIRUS 8-UNRELATED PRIMARY EFFUSION LYMPHOMA-LIKE LYMPHOMA IN A PATIENT WITH HEPATITIS B VIRUS-RELATED LIVER CIRRHOSIS: A CASE REPORT

 
 
Author(s):  FAN HE BIN*, YANG DONG LIANG, GUO YONG, CHEN AN SHEN, ZHOU MU XIU, WU JUAN JUAN, MA XIAO JU, LI ZHI
 
* DEPARTMENT OF INFECTIOUS DISEASE, THE PEOPLE'S LIBERATION ARMY 161HOSPITAL, WUHAN-430010, HUBEI PROVINCE, CHINA
 
Abstract: 

This study describes a rare case of Human Immunodeficiency Virus and Human Herpes Virus 8 (HHV-8) negative primary effusion lymphoma (PEL) -like lymphoma in a patient with hepatitis B virus-related liver cirrhosis, diagnosed in a 66-year-old male who rapidly progressed to a sense of abdominal fullness. Cytological analysis of the pleural effusion demonstrated large atypical lymphoid cells with rounded nuclei, prominent nucleoli, and abundant cytoplasm. Immunocytochemistry of the pleural effusion detected atypical CD20+lymphoid cells. The patient was hospitalized, and died following sepsis and multi-organ failure. Our case highlights that HHV-8-unrelated PEL-like lymphoma patients have different pathogenetic mechanisms of causality at the biological level, immunophenotype, clinical behavior, and prognosis.

 
Keyword(s): HEPATITIS B VIRUS, HUMAN HERPES VIRUS 8, LIVER CIRRHOSIS, PRIMARY EFFUSION LYMPHOMA
 
References: 
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