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Paper Information

Journal:   ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH)   Spring 2003 , Volume 5 , Number 1; Page(s) 1 To 11.
 
Paper: 

CORRELATION BETWEEN BONE MINERAL DENSITY AND OSTEOPOROSIS WITH CA AND VITAMIN D INTAKE

 
 
Author(s):  JAVADI E., HOSSEINNEZHAD ARASH, KHALILI-FARD A.R., ADIBI H., MAGHBOOLI Z., ARDESHIR LARIJANI MOHAMMAD BAGHER
 
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Abstract: 
Negative calcium balance, hypophosphatemia, and mild hypocalcemia occur in the absence of sufficient quantities of vitamin D. The purpose of this study is to investigate the influence of dietary calcium (Ca) and vitamin D (vit D) intake on those plasma levels and bone mineral density (BMD). .
A total of 830, 20-76 years- old healthy population (60.8% women, 39.2% men) of Tehran, from 50 clusters were randomly selected, following exclusion of people suffering from endocrine, rheumatologic or chronic diseases, fractures, other conditions or using drugs that affecting bone metabolism. Vit D and Ca intakes were assessed. with a food frequency questionnaire. Self-reported daily time of sun exposure was used to categorize exposure to sunshine all participations underwent clinical examination and lumbar spine and proximal of femur BMD by using dual-energy X-ray absorptiometry technique. Plasma level of 25(OH) D, Ca, Phosphate (P), alkaline phosphatase (ALK P), parathyroid hormone (PTH) measured during winter. The correlation between these results was investigated.
Mean of serum level vitamin D in men lower than women, as so Ca level of serum and intake of vit D and Ca in men higher than women. In the Logistic Regression, sex and parathyroid hormone were independent variables for serum of vit D variation.
In women older than 45 years, BMD in region of lumbar spine had significantly association with serum levels of parathyroid hormone. Also increasing parathyroid hormone had association with osteoporosis prevalence.
The mean of Ca intake in osteoporotic patients was lower than other subjects. In men younger than 40 years that had Ca intake more than 19gram/day, lumbar spine BMD was significantly higher than others with lower Ca consumption. Vitamin D intake had significantly association with osteoporosis in men.
In adequate calcium intake may translate into inadequate calcium retention and a reduction in peak bone mass. The high prevalence of 25 (OH) D deficiency indicate that vit D be obtained from solar irradiation and dietary sources appears inadequate.
 
Keyword(s): OSTEOPOROSIS, BONE MINERAL DENSITY, INTAKE CALCIUM, INTAKE VITAMIN
 
References: 
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