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Paper Information

Journal:   YAFTEH   Fall 2004 , Volume 6 , Number 22; Page(s) 31 To 36.
 
Paper: 

A STUDY OF CHANGES IN SOME SERUM METABOLIC PARAMETERS DUE TO DEPOT MEDROXY PROGESTRON ACETAT

 
 
Author(s):  ABBAS ALIPOUR KABIREH ROGHIEH, MAHJOUB H.
 
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Abstract: 

Background: A progestogen-only contraceptive is using of Medroxy progesterone acetate, which prevent-inhibits ovulation for several months. The purpose of this study was to evaluate changes in metabolic parameters after three and six month use of Depot Medroxy progesterone Acetate (DMPA) in female volunteers.
Materials and methods: Triglyceride, Cholesterol, HDL-Cholesterol and LDL cholesterol of the twenty one of volunteers for DMPA acceptors for the first time in the Hamedan Shohada infirmary, were detected every three-month. The data were analyzed using repeated measurement ANOVA by statistical package of SPSS.
Results: The results showed a significant decrease in serum Cholesterol and LDL Cholesterol (P<0.00l) also, HDL-cholesterol was increased (P=0.045), but there were no statistically significant changes in serum Triglyceride during 6 months of DMPA injection.
Conclusion: It can be concluded, there is no risk of arteriosclerosis for DMPA users, however, monitoring the lipid profile annually in women using DMPA for long duration is suggested.

 
Keyword(s): DEPOT MEDROXY PROGESTERONE ACETATE, LIPIDS AND LIPOPROTEIN, SERUM
 
References: 
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