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Paper Information

Journal:   JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE   2004 , Volume 25 , Number 45; Page(s) 17 To 25.
 
Paper: 

A COMPARISON OF 0.25% PETHIDINE VERSUS 0.5% LIDOCAINE IN INTRAVENOUS REGIONAL ANESTHESIA (IVRA) FOR UPPER EXTREMITY SURGERY

 
 
Author(s):  IMANI F., JAFARIAN ALI AKBAR
 
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Abstract: 

Intravenous regional anesthesia (IVRA) is a technique for providing anesthesia during extremity surgery. Lidocaine is one of local anesthetics which commonly used for IVRA. Pethidine (meperidine) has been shown to have weak local anesthetic properties. The aim of this study was to evaluate whether pethidine alone, compared to lid6caine, produce sufficient anesthesia during intravenous regional anesthesia.
50 ASA I-II adult patients undergoing orthopedic surgery for upper extremity received IVRA under double tourniquet condition with either pethidine or lidocaine. Patients were randomly assigned to one of two groups: P group received 40ml and L group received 40ml 0.5% lidocaine. Onset of sensory and motor block, sensory and motor block recovery times, pain score after tourniquet released, total midazolam and sufentanil doses during surgery and recovery room, and incidnece of adverse effects were recorded.
Onset of sensory and motor block in P group was slower than L group. Sensory block recovery time was more prolonged in P than L group, but not significant difference in motor block recovery time. Average doses of sufentanil and midazolam administrated during surgery in P and L groups were no significant differences, but sufentanil administrated during recovery room was lower in P than L group. Pain score at first 30 min after tourniquet released in P group was lower than L group. Some side effects was more in P group and some was more in L group.
Our study showed that the pethidine as sole anesthetic in IVRA can not be first choice drug, but when lidocaine be contraindicated, pethidine can be alternative drug and produce acceptable anesthetic condition.

 
Keyword(s): PETHIDINE, LIDOCAINE, INTRAVENOUS REGIONAL ANESTHESIA
 
References: 
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