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Paper Information

Journal:   SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES   Winter 2001 , Volume 5 , Number 2; Page(s) 1 To 6.
 
Paper: 

THE EFFECTS OF AEROBIC EXERCISE ON BODY IRON INDICES IN NORMAL SUBJECTS AND IN PATIENTS WITH THALASSEMIA MAJOR

 
 
Author(s):  ZAREZADEH Y.*, EBRAHIMI E., GHAYDARI M.E., AMANI A., JALILI A.
 
* Kurdistan University of Medical Sciences, Sanandaj, Corres
 
Abstract: 
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INTRODUCTION: Iron overload is the most important complication in patients with thalassemia major. This study was aimed to identify the effects of a standard exercise on body iron indices in the patients with thalassemia major and in normal subjects in Sanandaj during 1999.
MATERIALS & METHODS: This was a quasi-experimental study. The subjects were 32 patients with thalassemia major and 30 normal persons. The range of age in the both groups was 8-20 years. They were exercised by treadmill. Blood samples were obtained before exercise, immediatly after and 48 hours following the exercise. Then, serum iron, ferritin and TIBC were measured in all samples.
RESULTS: In both groups, the body iron indices showed significant changes in both samples following exercise as comparing to pre-exercise values. These changes were identical in both sex. In both groups, serum iron and ferritin decreased and serum TIBC increased immediatly following aerobic exercise. However, all of them significanlty increased 48 hours after exercise as comparing to pre-exercise valuses.
CONCLUSIONS: Regarding our study, regular exercise may be useful in the patients with thalassemia major if further studies confirm the effects of exercise (particularly in multiple courses) in decreasing iron overload. Further evaluation about iron deficiency anemia in athletes (specialy in heavy sports) is also recommended.
 
Keyword(s): THALASSEMIA MAJOR, IRON, FERITIN, TIBC, EXERCISE
 
References: 
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