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Paper Information

Journal:   JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)   Fall-Winter 2003 , Volume 20 , Number 67; Page(s) 57 To 64.
 
Paper: 

THE ASSOCIATION OF CALCIUM AND BLOOD PRESSURE IN ADULTS OF ISFAHAN CITY

 
 
Author(s):  RAFIEI M., BOSHTAM M., SARAFZADEGAN NAZILA, VAKILI R., GOLSHADI I., SEIRAFIAN SH.
 
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Abstract: 
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Introduction: Regarding the high prevalence of hypertension in Isfahan population, a research aimed studying the association of blood pressure with electrolytes was done. In this issue, the amount of 24-hour urinary and dietary calcium, and their relationship with blood pressure has been presented.
Methods: This study carried out on 1800 people (20-60 years old) selected by multistage sampling from Isfahan population (850 men, 950 women). For each person, a special questionnaire was completed regarding personal characteristics; cardiovascular risk factors, smoking, medication, etc. At the same time, the blood pressure was measured twice by WHO standardized method. Also, heart rate was recorded. The 24-hr urine was collected in graded container. This process was repeated three times. The measurments of choloride, sodium, calcium and potassium concentrations were done through flame photometry. Of course, those people with kidney failure or dietary salt restriction were excluded. Also, the concentration of urinary creatinine was measured as an indicator for verifying urine to be collected through the past 24 hours. Then, false samples were excluded from analysis. The obtained data was analysed using t test, ANOVA and multiregression analysis by SPSS/WIN.
Results: The obtained results show that the mean value of dietary calcium intake was 530.45±231.8 mg/day in people aged 20-60years old (665.0±248.1 gr/day in men and 467. 7±186.4 mg/day in women) that is lower than the recommended value.5 (1000-1200 mg/day). Also, the urinary calcium was estimated as 113±48 mmol/24 hr urine in total population that this mean value was 112.1 ±52.7 mg/24-hr urine in women and 109.4 ±43.2 mg/24-hr urine in men (P=0.57). Also, the a5sociation of systolic and diastolic blood pressures with urinary and dietary calcium was studied but there was significant relationship neither in normotensive nor hypertensive subjects (P>0.05).
Discussion: Therefore, although any significant relaitonship did not obtain between calcium and blood pressure in our society, it must be recommended to people to consider dietary source of calcium in their diet more than before due to this low consumed calcium and its probably resulted health hazards. Also, performing interventional, studies is essential for proving a critical association
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