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Paper Information

Journal:   IRANIAN JOURNAL OF OTORHINOLARYNGOLOGY   Spring 2004 , Volume 16 , Number 1 (35); Page(s) 57 To 62.
 
Paper: 

PAPILLARY CARCINOMA OF THYROGLOSSAL DUCT CYST: A CASE REPORT

 
 
Author(s):  GHIASI T., GHANADAN A.R., ZIAOLHAGH R., GHAFARZADEGAN KAMRAN, ZOJAJI R.
 
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Abstract: 
The thyroglossal duct cyst (TOC) is the most common anomaly observed during thyroid development, but carcinoma is found in approximately 1% of these lesions. To date, approximately 250 cases have been reported, the majority of them being papillary carcinoma (PC). The cysts are usually asymptomatic. The presentation of the patient with carcinomais similar to TOC. The case we are reporting is a 36-years-old man who had been exposedto chemical warfare agents during the Iraq-Iran war. He presented with a cystic nodule above the thyroid, and the diagnosis of TOC was made during operation. Histopathologic examination reveald PC in a TOC. Although thyroid examination and scan were normal, because of exposure to chemical warfare agents, total thyroidectomy was performed and reveald multifocal PC of the thyroid. Therefore, exposure to chemical warfare agents can be a high risk factor for thyroid malignancy, and total thyroidectomy in every case of PC to TOC with a history of chemical warfare injury is recommended.
 
Keyword(s): THYROGLOSSAL DUCT CYST, PAPILLARY CARCINOMA, MUSTARD GAS
 
References: 
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